Strain SummaryC.129S2-Trp53tm1Tyj/+

Strain Name

C.129S2-Trp53tm1Tyj/+

Strain Type(s)

congenic  •  targeted mutation (knockout)

Strain Synonym(s)

Trp53-/+  •  Trp53-/+ BALB/c

Description

Heterozygous mice. The mutation had been backcrossed onto a BALB/cJ genetic background. The mutation was generated in a 129S2/SvPas genetic background.

Strain Genetics

Trp53tm1Tyj / Trp53+

Models

6 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Blood vessel hemangiosarcoma Blood vessel

low

References: Cellurale C, PLoS One 2010;5(8):

Leukocyte lymphoma Leukocyte

low

References: Cellurale C, PLoS One 2010;5(8):

Mammary gland carcinoma Mammary gland

43

References: Cellurale C, PLoS One 2010;5(8):

Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast

low

References: Cellurale C, PLoS One 2010;5(8):

(Unspecified organ) carcinoma (Unspecified organ)

high

References: Cellurale C, PLoS One 2010;5(8):

(Unspecified organ) tumor (Unspecified organ)

100

References: Cellurale C, PLoS One 2010;5(8):