Strain SummaryC.129S2-Trp53tm1Tyj/+
Strain Name |
C.129S2-Trp53tm1Tyj/+ |
Strain Type(s) |
congenic • targeted mutation (knockout) |
Strain Synonym(s) |
Trp53-/+ • Trp53-/+ BALB/c |
Description |
Heterozygous mice. The mutation had been backcrossed onto a BALB/cJ genetic background. The mutation was generated in a 129S2/SvPas genetic background. |
Strain Genetics |
Trp53tm1Tyj / Trp53+ |
Frequency | ||||||||
---|---|---|---|---|---|---|---|---|
Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
Blood vessel hemangiosarcoma | Blood vessel |
low |
References: Cellurale C, PLoS One 2010;5(8): |
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Leukocyte lymphoma | Leukocyte |
low |
References: Cellurale C, PLoS One 2010;5(8): |
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Mammary gland carcinoma | Mammary gland |
43 |
References: Cellurale C, PLoS One 2010;5(8): |
|||||
Mesodermal cell/mesoblast sarcoma | Mesodermal cell/mesoblast |
low |
References: Cellurale C, PLoS One 2010;5(8): |
|||||
(Unspecified organ) carcinoma | (Unspecified organ) |
high |
References: Cellurale C, PLoS One 2010;5(8): |
|||||
(Unspecified organ) tumor | (Unspecified organ) |
100 |
References: Cellurale C, PLoS One 2010;5(8): |