Strain SummaryC57BL/6J-Apc^Min/+

Strain Name	C57BL/6J-Apc^Min/+
Strain Type(s)	chemically induced mutation
Strain Synonym(s)	Apc^Min • Apc^Min/+ • APC^min/+ • APC^Min/+ • APC^Min/+ • B6-Apc^Min • B6-Apc^Min/Apc⁺ • B6 Min/+ • C57BL/6 Apc^Min/+ • C57Bl/6-Min • C57BL/6-Min • C57BL/6J-Apc^Min/+ • C57BL/6J-APC^Min/+ • C57BL/6J/-Apc^Min • C57BL/6J-APC^min/+ • C57BL/6J-Apc^Min/J • C57BL/6J Apc^Min/+ • C57BL/6J-Apc^Min/+ • C57BL/6J APC^Min/+ • C57BL/6J Apc^min • C57BL/6J-Apc^Min • C57BL/6J Apc^Min/+ • C57BL/6J-Apc^Min • C57BL/6J-Apc^Min/+ • C57BL/6J-APC^Min/+ • C57BL/6J-Apc^Min/J • C57Bl/6J-Min/+ • C57BL/6J Min • C57BL/6J Min/+ • C57BL/6J-Min • C57BL/6J-Min/+ • C57BL/6J/Min/+ • C57Bl/6J-Min+ • C57BL/6J Min • C57BL/6J Min /+ • C57BL/6J-Min/+ • C57Bl/6J^Min/+ • C57Bl/6-Min/+ • C57BL/6-Min • adenomatous polyposis coli^Min/+ • Apc+/- • Apc+/- Msh2+/+ • Apc^Min/+ • Apc^Min/+ • APC^Min/+ • Apc^min • Apc^Min • Apc^Min heterozygous • ApcMin • Apc^Min/Apc⁺ • Apc^Min • Apc^Min/+ • APC^Min/+ • Min • Min/+ • Min C57BL/6J • Min/+ C57BL/6J • Min • Min/+ • multiple intestinal neoplasia
Description	Heterozygous mice - "Min" mutation
Strain Links	• JAX Mice
Strain Genetics	List all models in MMHCdb carrying the Apc^Min allele Apc^Min / Apc⁺

Models
211 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Intestine - Large Intestine - Colon adenocarcinoma	Intestine - Large Intestine - Colon	BRL-49,653, PPAR gamma ligand		observed			References: Lefebvre AM, Nat Med 1998 Sep;4(9):1053-7
Intestine - Large Intestine - Colon adenoma	Intestine - Large Intestine - Colon			observed - 100	observed - 100	0 - observed	References: Andrijes R, Proc Natl Acad Sci U S A 2021 Sep 28;118(39): ⋅ Bjerknes M, Am J Pathol 1999 Jun;154(6):1831-4 ⋅ Chen Q, Life Sci Alliance 2021 Mar;4(3): ⋅ Ritland SR, Cancer Res 2000 Sep 1;60(17):4678-81 ⋅ Schmelz EM, Cancer Res 2001 Sep 15;61(18):6723-9 ⋅ Shattuck-Brandt RL, Mol Carcinog 1999 Mar;24(3):177-87 ⋅ Wilson CL, Proc Natl Acad Sci U S A 1997 Feb 18;94(4):1402-7 ⋅ Woo DK, Am J Pathol 2012 Jan;180(1):24-31 ⋅ Xie G, JCI Insight 2022 Feb 22;7(4):e150894 3 pathology image(s)
Intestine - Large Intestine - Colon adenoma	Intestine - Large Intestine - Colon	N-[4-(3-chloro-4-fluoro-phenylamino)-quinazolin-6-yl]acrylamide (CFPQA)			observed		References: Ritland SR, Cancer Res 2000 Sep 1;60(17):4678-81
Intestine - Large Intestine - Colon adenoma	Intestine - Large Intestine - Colon	ceramide (N-palmitoylsphingosine)		observed			References: Schmelz EM, Cancer Res 2001 Sep 15;61(18):6723-9
Intestine - Large Intestine - Colon adenoma	Intestine - Large Intestine - Colon	sphingolipid mix		observed			References: Schmelz EM, Cancer Res 2001 Sep 15;61(18):6723-9
Intestine - Large Intestine - Colon adenoma	Intestine - Large Intestine - Colon	sphingolipid mix ⋅ ceramide (N-palmitoylsphingosine)		observed			References: Schmelz EM, Cancer Res 2001 Sep 15;61(18):6723-9
Intestine - Large Intestine - Colon adenoma	Intestine - Large Intestine - Colon	piroxicam			observed		References: Ritland SR, Cancer Res 2000 Sep 1;60(17):4678-81
Intestine - Large Intestine - Colon adenoma - dysplastic	Intestine - Large Intestine - Colon	tamoxifen (for inducing expression from mutant alleles)				observed	References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23
Intestine - Large Intestine - Colon adenoma - tubular	Intestine - Large Intestine - Colon			observed			References: Lefebvre AM, Nat Med 1998 Sep;4(9):1053-7
Intestine - Large Intestine - Colon adenoma - tubular	Intestine - Large Intestine - Colon	tamoxifen (for inducing expression from mutant alleles)				observed	References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23
Intestine - Large Intestine - Colon dysplasia - high grade	Intestine - Large Intestine - Colon					0	References: Andrijes R, Proc Natl Acad Sci U S A 2021 Sep 28;118(39):
Intestine - Large Intestine - Colon dysplasia - low grade	Intestine - Large Intestine - Colon					15.79	References: Andrijes R, Proc Natl Acad Sci U S A 2021 Sep 28;118(39):
Intestine - Large Intestine - Colon foci - aberrant crypt (ACF)	Intestine - Large Intestine - Colon	2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)			observed - 93		References: Steffensen IL, Cancer Res 2001 Dec 15;61(24):8689-96
Intestine - Large Intestine - Colon foci - aberrant crypt (ACF)	Intestine - Large Intestine - Colon				86 - 90	observed	References: Steffensen IL, Cancer Res 2001 Dec 15;61(24):8689-96 ⋅ Zheng W, Int J Cancer 2012 Jan 1;130(1):10-9
Intestine - Large Intestine - Colon polyp	Intestine - Large Intestine - Colon	polyethylene glycol		observed			References: Shailubhai K, Cancer Res 2000 Sep 15;60(18):5151-7
Intestine - Large Intestine - Colon polyp	Intestine - Large Intestine - Colon	uroguanylin ⋅ polyethylene glycol		0 - observed			References: Shailubhai K, Cancer Res 2000 Sep 15;60(18):5151-7
Intestine - Large Intestine - Colon polyp	Intestine - Large Intestine - Colon		observed			observed - 90.91	References: Andrijes R, Proc Natl Acad Sci U S A 2021 Sep 28;118(39): ⋅ Gupta RA, Nat Med 2004 Mar;10(3):245-7 ⋅ Mutoh M, Cancer Res 2002 Jan 1;62(1):28-32 ⋅ Zeineldin M, Oncogene 2012 May 10;31(19):2423-37
Intestine - Large Intestine - Colon polyp	Intestine - Large Intestine - Colon	2-[2-{2-(1-naphthyl)propanoylamino}phenyl]methylbenzoic acid (ONO-AE2-227)	observed				References: Mutoh M, Cancer Res 2002 Jan 1;62(1):28-32
Intestine - Large Intestine - Colon polyp	Intestine - Large Intestine - Colon	GW501516, PPAR-delta agonist				observed	References: Gupta RA, Nat Med 2004 Mar;10(3):245-7
Intestine - Large Intestine - Colon tumor	Intestine - Large Intestine - Colon	low fiber			100		References: Pierre F, Cancer Res 1997 Jan 15;57(2):225-8
Intestine - Large Intestine - Colon tumor	Intestine - Large Intestine - Colon	high fiber			60 - 100		References: Pierre F, Cancer Res 1997 Jan 15;57(2):225-8
Intestine - Large Intestine - Colon tumor	Intestine - Large Intestine - Colon		observed	observed	observed - 45	observed	References: Barnes CJ, Gastroenterology 1998 May;114(5):873-7 ⋅ Lefebvre AM, Nat Med 1998 Sep;4(9):1053-7 ⋅ Ma H, Cell Rep 2020 Jan 21;30(3):793-806.e6 ⋅ Mahmoud NN, Carcinogenesis 1999 Feb;20(2):299-303 ⋅ Ritland SR, Clin Cancer Res 1999 Apr;5(4):855-63 ⋅ Shattuck-Brandt RL, Gastroenterology 2000 Feb;118(2):337-45 ⋅ Steffensen IL, Cancer Res 2001 Dec 15;61(24):8689-96 ⋅ Weyant MJ, Cancer Res 2001 Jan 1;61(1):118-25 ⋅ Weyant MJ, Cancer Res 2001 Mar 15;61(6):2547-51
Intestine - Large Intestine - Colon tumor	Intestine - Large Intestine - Colon	chenodeoxycholate (chenodeoxycholic acid)	observed				References: Mahmoud NN, Carcinogenesis 1999 Feb;20(2):299-303
Intestine - Large Intestine - Colon tumor	Intestine - Large Intestine - Colon	sulfasalazine (SASP)			observed		References: Ritland SR, Clin Cancer Res 1999 Apr;5(4):855-63
Intestine - Large Intestine - Colon tumor	Intestine - Large Intestine - Colon	Pentasa			observed		References: Ritland SR, Clin Cancer Res 1999 Apr;5(4):855-63
Intestine - Large Intestine - Colon tumor	Intestine - Large Intestine - Colon	5-aminosalicylic acid, free acid (5-ASA)			observed		References: Ritland SR, Clin Cancer Res 1999 Apr;5(4):855-63
Intestine - Large Intestine - Colon tumor	Intestine - Large Intestine - Colon	(+)-catechin	observed				References: Weyant MJ, Cancer Res 2001 Jan 1;61(1):118-25
Intestine - Large Intestine - Colon tumor	Intestine - Large Intestine - Colon	ovariectomy	observed				References: Weyant MJ, Cancer Res 2001 Mar 15;61(6):2547-51
Intestine - Large Intestine - Colon tumor	Intestine - Large Intestine - Colon	17beta-estradiol (E2) ⋅ ovariectomy	observed				References: Weyant MJ, Cancer Res 2001 Mar 15;61(6):2547-51
Intestine - Large Intestine - Colon tumor	Intestine - Large Intestine - Colon	2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)			observed - 88		References: Steffensen IL, Cancer Res 2001 Dec 15;61(24):8689-96
Intestine - Large Intestine - Colon tumor	Intestine - Large Intestine - Colon	BRL-49,653, PPAR gamma ligand		observed			References: Lefebvre AM, Nat Med 1998 Sep;4(9):1053-7
Intestine - Large Intestine - Colon tumor	Intestine - Large Intestine - Colon	troglitazone		observed			References: Lefebvre AM, Nat Med 1998 Sep;4(9):1053-7
Intestine - Large Intestine - Colon tumor	Intestine - Large Intestine - Colon	aspirin (acetylsalicylic acid) (ASA)			observed		References: Barnes CJ, Gastroenterology 1998 May;114(5):873-7
Intestine - Large Intestine - Colon tumor	Intestine - Large Intestine - Colon	tamoxifen (for inducing expression from mutant alleles)				observed	References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23
Intestine - Large Intestine - Rectum tumor	Intestine - Large Intestine - Rectum			observed			References: Ma H, Cell Rep 2020 Jan 21;30(3):793-806.e6
Intestine - Large Intestine adenocarcinoma	Intestine - Large Intestine			0			References: Pino MV, Toxicol Pathol 2004 Jan-Feb;32(1):58-63
Intestine - Large Intestine adenocarcinoma	Intestine - Large Intestine	NID525, PPAR gamma agonist		0			References: Pino MV, Toxicol Pathol 2004 Jan-Feb;32(1):58-63
Intestine - Large Intestine adenocarcinoma	Intestine - Large Intestine	troglitazone		6.7			References: Pino MV, Toxicol Pathol 2004 Jan-Feb;32(1):58-63
Intestine - Large Intestine adenocarcinoma	Intestine - Large Intestine	pioglitazone		0			References: Pino MV, Toxicol Pathol 2004 Jan-Feb;32(1):58-63
Intestine - Large Intestine adenocarcinoma	Intestine - Large Intestine	rosiglitazone		0			References: Pino MV, Toxicol Pathol 2004 Jan-Feb;32(1):58-63
Intestine - Large Intestine adenoma	Intestine - Large Intestine		observed - 54	60 - 67			References: Nakatsugi S, Jpn J Cancer Res 1997 Dec;88(12):1117-20 ⋅ Paulsen JE, Carcinogenesis 1997 Oct;18(10):1905-10 ⋅ Pino MV, Toxicol Pathol 2004 Jan-Feb;32(1):58-63
Intestine - Large Intestine adenoma	Intestine - Large Intestine	fish oil	25 - 33	50 - 60			References: Paulsen JE, Carcinogenesis 1997 Oct;18(10):1905-10
Intestine - Large Intestine adenoma	Intestine - Large Intestine	sulindac	10				References: Boolbol SK, Cancer Res 1996 Jun 1;56(11):2556-60
Intestine - Large Intestine adenoma	Intestine - Large Intestine	NID525, PPAR gamma agonist		100			References: Pino MV, Toxicol Pathol 2004 Jan-Feb;32(1):58-63
Intestine - Large Intestine adenoma	Intestine - Large Intestine	troglitazone		observed			References: Pino MV, Toxicol Pathol 2004 Jan-Feb;32(1):58-63
Intestine - Large Intestine adenoma	Intestine - Large Intestine	pioglitazone		100			References: Pino MV, Toxicol Pathol 2004 Jan-Feb;32(1):58-63
Intestine - Large Intestine adenoma	Intestine - Large Intestine	rosiglitazone		100			References: Pino MV, Toxicol Pathol 2004 Jan-Feb;32(1):58-63
Intestine - Large Intestine adenoma	Intestine - Large Intestine	nimesulide (4-nitro-2-phenoxymethanesulfonanilide)	observed				References: Nakatsugi S, Jpn J Cancer Res 1997 Dec;88(12):1117-20
Intestine - Large Intestine hyperplasia	Intestine - Large Intestine			observed			References: Pino MV, Toxicol Pathol 2004 Jan-Feb;32(1):58-63
Intestine - Large Intestine hyperplasia	Intestine - Large Intestine	NID525, PPAR gamma agonist		observed			References: Pino MV, Toxicol Pathol 2004 Jan-Feb;32(1):58-63
Intestine - Large Intestine hyperplasia	Intestine - Large Intestine	troglitazone		observed			References: Pino MV, Toxicol Pathol 2004 Jan-Feb;32(1):58-63
Intestine - Large Intestine hyperplasia	Intestine - Large Intestine	pioglitazone		observed			References: Pino MV, Toxicol Pathol 2004 Jan-Feb;32(1):58-63
Intestine - Large Intestine hyperplasia	Intestine - Large Intestine	rosiglitazone		observed			References: Pino MV, Toxicol Pathol 2004 Jan-Feb;32(1):58-63
Intestine - Large Intestine polyp	Intestine - Large Intestine					observed - very low	References: Andrijes R, Proc Natl Acad Sci U S A 2021 Sep 28;118(39): ⋅ Gupta RA, Nat Med 2004 Mar;10(3):245-7 ⋅ Sundberg J, Personal Communication 1997;(): 2 pathology image(s)
Intestine - Large Intestine tumor	Intestine - Large Intestine		observed - 43	observed - 100	77.78	observed	References: Boolbol SK, Cancer Res 1996 Jun 1;56(11):2556-60 ⋅ Ma H, Cell Rep 2020 Jan 21;30(3):793-806.e6 ⋅ Steffensen IL, Carcinogenesis 1997 May;18(5):1049-54 ⋅ Ton-That H, FEBS Lett 1997 Dec 15;419(2-3):239-43 ⋅ Ziegler CC, J Nutr 2004 Jan;134(1):5-10
Intestine - Large Intestine tumor	Intestine - Large Intestine	2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)	14	50			References: Steffensen IL, Carcinogenesis 1997 May;18(5):1049-54
Intestine - Large Intestine tumor	Intestine - Large Intestine	troglitazone		93			References: Pino MV, Toxicol Pathol 2004 Jan-Feb;32(1):58-63
Intestine - Large Intestine tumor	Intestine - Large Intestine	resveratrol		observed			References: Ziegler CC, J Nutr 2004 Jan;134(1):5-10
Intestine - Small Intestine - Distal adenoma	Intestine - Small Intestine - Distal		observed	observed - 100			References: Nakatsugi S, Jpn J Cancer Res 1997 Dec;88(12):1117-20 ⋅ Pino MV, Toxicol Pathol 2004 Jan-Feb;32(1):58-63 ⋅ Schmelz EM, Cancer Res 2001 Sep 15;61(18):6723-9
Intestine - Small Intestine - Distal adenoma	Intestine - Small Intestine - Distal	ceramide (N-palmitoylsphingosine)		observed			References: Schmelz EM, Cancer Res 2001 Sep 15;61(18):6723-9
Intestine - Small Intestine - Distal adenoma	Intestine - Small Intestine - Distal	sphingolipid mix		observed			References: Schmelz EM, Cancer Res 2001 Sep 15;61(18):6723-9
Intestine - Small Intestine - Distal adenoma	Intestine - Small Intestine - Distal	sphingolipid mix ⋅ ceramide (N-palmitoylsphingosine)		observed			References: Schmelz EM, Cancer Res 2001 Sep 15;61(18):6723-9
Intestine - Small Intestine - Distal adenoma	Intestine - Small Intestine - Distal	NID525, PPAR gamma agonist		100			References: Pino MV, Toxicol Pathol 2004 Jan-Feb;32(1):58-63
Intestine - Small Intestine - Distal adenoma	Intestine - Small Intestine - Distal	nimesulide (4-nitro-2-phenoxymethanesulfonanilide)	observed				References: Nakatsugi S, Jpn J Cancer Res 1997 Dec;88(12):1117-20
Intestine - Small Intestine - Distal polyp	Intestine - Small Intestine - Distal		observed				References: Mutoh M, Cancer Res 2002 Jan 1;62(1):28-32
Intestine - Small Intestine - Distal polyp	Intestine - Small Intestine - Distal	2-[2-{2-(1-naphthyl)propanoylamino}phenyl]methylbenzoic acid (ONO-AE2-227)	observed				References: Mutoh M, Cancer Res 2002 Jan 1;62(1):28-32
Intestine - Small Intestine - Distal tumor	Intestine - Small Intestine - Distal	2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)			observed		References: Steffensen IL, Cancer Res 2001 Dec 15;61(24):8689-96
Intestine - Small Intestine - Distal tumor	Intestine - Small Intestine - Distal	BRL-49,653, PPAR gamma ligand		observed			References: Lefebvre AM, Nat Med 1998 Sep;4(9):1053-7
Intestine - Small Intestine - Distal tumor	Intestine - Small Intestine - Distal		observed	observed	observed		References: Barnes CJ, Gastroenterology 1998 May;114(5):873-7 ⋅ Lefebvre AM, Nat Med 1998 Sep;4(9):1053-7 ⋅ Xie G, JCI Insight 2022 Feb 22;7(4):e150894
Intestine - Small Intestine - Distal tumor	Intestine - Small Intestine - Distal	troglitazone		observed - 100			References: Lefebvre AM, Nat Med 1998 Sep;4(9):1053-7 ⋅ Pino MV, Toxicol Pathol 2004 Jan-Feb;32(1):58-63
Intestine - Small Intestine - Distal tumor	Intestine - Small Intestine - Distal	pioglitazone		100			References: Pino MV, Toxicol Pathol 2004 Jan-Feb;32(1):58-63
Intestine - Small Intestine - Distal tumor	Intestine - Small Intestine - Distal	rosiglitazone		100			References: Pino MV, Toxicol Pathol 2004 Jan-Feb;32(1):58-63
Intestine - Small Intestine - Distal tumor	Intestine - Small Intestine - Distal	aspirin (acetylsalicylic acid) (ASA)			observed		References: Barnes CJ, Gastroenterology 1998 May;114(5):873-7
Intestine - Small Intestine - Duodenum adenoma	Intestine - Small Intestine - Duodenum	piroxicam			observed		References: Ritland SR, Cancer Res 2000 Sep 1;60(17):4678-81
Intestine - Small Intestine - Duodenum adenoma	Intestine - Small Intestine - Duodenum	N-[4-(3-chloro-4-fluoro-phenylamino)-quinazolin-6-yl]acrylamide (CFPQA)			observed		References: Ritland SR, Cancer Res 2000 Sep 1;60(17):4678-81
Intestine - Small Intestine - Duodenum adenoma	Intestine - Small Intestine - Duodenum				observed		References: Ritland SR, Cancer Res 2000 Sep 1;60(17):4678-81
Intestine - Small Intestine - Duodenum lesion	Intestine - Small Intestine - Duodenum	N-[4-(3-chloro-4-fluoro-phenylamino)-quinazolin-6-yl]acrylamide (CFPQA)			0 - observed		References: Ritland SR, Cancer Res 2000 Sep 1;60(17):4678-81
Intestine - Small Intestine - Duodenum polyp	Intestine - Small Intestine - Duodenum	polyethylene glycol		observed			References: Shailubhai K, Cancer Res 2000 Sep 15;60(18):5151-7
Intestine - Small Intestine - Duodenum polyp	Intestine - Small Intestine - Duodenum	uroguanylin ⋅ polyethylene glycol		observed			References: Shailubhai K, Cancer Res 2000 Sep 15;60(18):5151-7
Intestine - Small Intestine - Duodenum polyp	Intestine - Small Intestine - Duodenum					45.45	References: Zeineldin M, Oncogene 2012 May 10;31(19):2423-37
Intestine - Small Intestine - Duodenum tumor	Intestine - Small Intestine - Duodenum		observed			observed	References: Boolbol SK, Cancer Res 1996 Jun 1;56(11):2556-60 ⋅ Mahmoud NN, Carcinogenesis 1999 Feb;20(2):299-303 ⋅ Sun X, Mol Cancer 2009;8():73 ⋅ Weyant MJ, Cancer Res 2001 Jan 1;61(1):118-25 ⋅ Weyant MJ, Cancer Res 2001 Mar 15;61(6):2547-51
Intestine - Small Intestine - Duodenum tumor	Intestine - Small Intestine - Duodenum	chenodeoxycholate (chenodeoxycholic acid)	observed				References: Mahmoud NN, Carcinogenesis 1999 Feb;20(2):299-303
Intestine - Small Intestine - Duodenum tumor	Intestine - Small Intestine - Duodenum	sulindac	0				References: Boolbol SK, Cancer Res 1996 Jun 1;56(11):2556-60
Intestine - Small Intestine - Duodenum tumor	Intestine - Small Intestine - Duodenum	polyethylene glycol		30			References: Shailubhai K, Cancer Res 2000 Sep 15;60(18):5151-7
Intestine - Small Intestine - Duodenum tumor	Intestine - Small Intestine - Duodenum	(+)-catechin	observed				References: Weyant MJ, Cancer Res 2001 Jan 1;61(1):118-25
Intestine - Small Intestine - Duodenum tumor	Intestine - Small Intestine - Duodenum	ovariectomy	observed				References: Weyant MJ, Cancer Res 2001 Mar 15;61(6):2547-51
Intestine - Small Intestine - Duodenum tumor	Intestine - Small Intestine - Duodenum	17beta-estradiol (E2) ⋅ ovariectomy	observed				References: Weyant MJ, Cancer Res 2001 Mar 15;61(6):2547-51
Intestine - Small Intestine - Ileum adenoma	Intestine - Small Intestine - Ileum			observed	observed		References: Paoni NF, Physiol Genomics 2003 Nov 11;15(3):228-35 ⋅ Ritland SR, Cancer Res 2000 Sep 1;60(17):4678-81
Intestine - Small Intestine - Ileum adenoma	Intestine - Small Intestine - Ileum	N-[4-(3-chloro-4-fluoro-phenylamino)-quinazolin-6-yl]acrylamide (CFPQA)			observed		References: Ritland SR, Cancer Res 2000 Sep 1;60(17):4678-81
Intestine - Small Intestine - Ileum adenoma	Intestine - Small Intestine - Ileum	piroxicam			observed		References: Ritland SR, Cancer Res 2000 Sep 1;60(17):4678-81
Intestine - Small Intestine - Ileum carcinoma	Intestine - Small Intestine - Ileum			observed			References: Paoni NF, Physiol Genomics 2003 Nov 11;15(3):228-35
Intestine - Small Intestine - Ileum polyp	Intestine - Small Intestine - Ileum	uroguanylin ⋅ polyethylene glycol		observed			References: Shailubhai K, Cancer Res 2000 Sep 15;60(18):5151-7
Intestine - Small Intestine - Ileum polyp	Intestine - Small Intestine - Ileum	polyethylene glycol		observed			References: Shailubhai K, Cancer Res 2000 Sep 15;60(18):5151-7
Intestine - Small Intestine - Ileum polyp	Intestine - Small Intestine - Ileum					100	References: Zeineldin M, Oncogene 2012 May 10;31(19):2423-37
Intestine - Small Intestine - Ileum tumor	Intestine - Small Intestine - Ileum		observed			observed	References: Boolbol SK, Cancer Res 1996 Jun 1;56(11):2556-60 ⋅ Sun X, Mol Cancer 2009;8():73
Intestine - Small Intestine - Ileum tumor	Intestine - Small Intestine - Ileum	sulindac	0				References: Boolbol SK, Cancer Res 1996 Jun 1;56(11):2556-60
Intestine - Small Intestine - Jejunum adenoma	Intestine - Small Intestine - Jejunum				observed		References: Ritland SR, Cancer Res 2000 Sep 1;60(17):4678-81
Intestine - Small Intestine - Jejunum adenoma	Intestine - Small Intestine - Jejunum	N-[4-(3-chloro-4-fluoro-phenylamino)-quinazolin-6-yl]acrylamide (CFPQA)			observed		References: Ritland SR, Cancer Res 2000 Sep 1;60(17):4678-81
Intestine - Small Intestine - Jejunum adenoma	Intestine - Small Intestine - Jejunum	piroxicam			observed		References: Ritland SR, Cancer Res 2000 Sep 1;60(17):4678-81
Intestine - Small Intestine - Jejunum polyp	Intestine - Small Intestine - Jejunum	uroguanylin ⋅ polyethylene glycol		observed			References: Shailubhai K, Cancer Res 2000 Sep 15;60(18):5151-7
Intestine - Small Intestine - Jejunum polyp	Intestine - Small Intestine - Jejunum	polyethylene glycol		observed			References: Shailubhai K, Cancer Res 2000 Sep 15;60(18):5151-7
Intestine - Small Intestine - Jejunum polyp	Intestine - Small Intestine - Jejunum					100	References: Zeineldin M, Oncogene 2012 May 10;31(19):2423-37
Intestine - Small Intestine - Jejunum tumor	Intestine - Small Intestine - Jejunum		observed			observed	References: Boolbol SK, Cancer Res 1996 Jun 1;56(11):2556-60 ⋅ Sun X, Mol Cancer 2009;8():73
Intestine - Small Intestine - Jejunum tumor	Intestine - Small Intestine - Jejunum	sulindac	0				References: Boolbol SK, Cancer Res 1996 Jun 1;56(11):2556-60
Intestine - Small Intestine - Medial adenoma	Intestine - Small Intestine - Medial		observed	observed			References: Nakatsugi S, Jpn J Cancer Res 1997 Dec;88(12):1117-20 ⋅ Schmelz EM, Cancer Res 2001 Sep 15;61(18):6723-9
Intestine - Small Intestine - Medial adenoma	Intestine - Small Intestine - Medial	ceramide (N-palmitoylsphingosine)		observed			References: Schmelz EM, Cancer Res 2001 Sep 15;61(18):6723-9
Intestine - Small Intestine - Medial adenoma	Intestine - Small Intestine - Medial	sphingolipid mix		observed			References: Schmelz EM, Cancer Res 2001 Sep 15;61(18):6723-9
Intestine - Small Intestine - Medial adenoma	Intestine - Small Intestine - Medial	sphingolipid mix ⋅ ceramide (N-palmitoylsphingosine)		observed			References: Schmelz EM, Cancer Res 2001 Sep 15;61(18):6723-9
Intestine - Small Intestine - Medial adenoma	Intestine - Small Intestine - Medial	nimesulide (4-nitro-2-phenoxymethanesulfonanilide)	observed				References: Nakatsugi S, Jpn J Cancer Res 1997 Dec;88(12):1117-20
Intestine - Small Intestine - Medial polyp	Intestine - Small Intestine - Medial		observed				References: Mutoh M, Cancer Res 2002 Jan 1;62(1):28-32
Intestine - Small Intestine - Medial polyp	Intestine - Small Intestine - Medial	2-[2-{2-(1-naphthyl)propanoylamino}phenyl]methylbenzoic acid (ONO-AE2-227)	observed				References: Mutoh M, Cancer Res 2002 Jan 1;62(1):28-32
Intestine - Small Intestine - Medial tumor	Intestine - Small Intestine - Medial	2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)			observed		References: Steffensen IL, Cancer Res 2001 Dec 15;61(24):8689-96
Intestine - Small Intestine - Medial tumor	Intestine - Small Intestine - Medial		observed	observed	observed		References: Barnes CJ, Gastroenterology 1998 May;114(5):873-7 ⋅ Xie G, JCI Insight 2022 Feb 22;7(4):e150894
Intestine - Small Intestine - Medial tumor	Intestine - Small Intestine - Medial	aspirin (acetylsalicylic acid) (ASA)			observed		References: Barnes CJ, Gastroenterology 1998 May;114(5):873-7
Intestine - Small Intestine - Proximal adenoma	Intestine - Small Intestine - Proximal		observed	observed - 100			References: Nakatsugi S, Jpn J Cancer Res 1997 Dec;88(12):1117-20 ⋅ Pino MV, Toxicol Pathol 2004 Jan-Feb;32(1):58-63 ⋅ Schmelz EM, Cancer Res 2001 Sep 15;61(18):6723-9
Intestine - Small Intestine - Proximal adenoma	Intestine - Small Intestine - Proximal	ceramide (N-palmitoylsphingosine)		observed			References: Schmelz EM, Cancer Res 2001 Sep 15;61(18):6723-9
Intestine - Small Intestine - Proximal adenoma	Intestine - Small Intestine - Proximal	sphingolipid mix		observed			References: Schmelz EM, Cancer Res 2001 Sep 15;61(18):6723-9
Intestine - Small Intestine - Proximal adenoma	Intestine - Small Intestine - Proximal	sphingolipid mix ⋅ ceramide (N-palmitoylsphingosine)		observed			References: Schmelz EM, Cancer Res 2001 Sep 15;61(18):6723-9
Intestine - Small Intestine - Proximal adenoma	Intestine - Small Intestine - Proximal	NID525, PPAR gamma agonist		100			References: Pino MV, Toxicol Pathol 2004 Jan-Feb;32(1):58-63
Intestine - Small Intestine - Proximal adenoma	Intestine - Small Intestine - Proximal	nimesulide (4-nitro-2-phenoxymethanesulfonanilide)	observed				References: Nakatsugi S, Jpn J Cancer Res 1997 Dec;88(12):1117-20
Intestine - Small Intestine - Proximal polyp	Intestine - Small Intestine - Proximal		observed				References: Mutoh M, Cancer Res 2002 Jan 1;62(1):28-32
Intestine - Small Intestine - Proximal polyp	Intestine - Small Intestine - Proximal	2-[2-{2-(1-naphthyl)propanoylamino}phenyl]methylbenzoic acid (ONO-AE2-227)	observed				References: Mutoh M, Cancer Res 2002 Jan 1;62(1):28-32
Intestine - Small Intestine - Proximal tumor	Intestine - Small Intestine - Proximal	2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)			observed		References: Steffensen IL, Cancer Res 2001 Dec 15;61(24):8689-96
Intestine - Small Intestine - Proximal tumor	Intestine - Small Intestine - Proximal	BRL-49,653, PPAR gamma ligand		observed			References: Lefebvre AM, Nat Med 1998 Sep;4(9):1053-7
Intestine - Small Intestine - Proximal tumor	Intestine - Small Intestine - Proximal		observed	observed	observed		References: Barnes CJ, Gastroenterology 1998 May;114(5):873-7 ⋅ Lefebvre AM, Nat Med 1998 Sep;4(9):1053-7 ⋅ Xie G, JCI Insight 2022 Feb 22;7(4):e150894
Intestine - Small Intestine - Proximal tumor	Intestine - Small Intestine - Proximal	troglitazone		observed - 100			References: Lefebvre AM, Nat Med 1998 Sep;4(9):1053-7 ⋅ Pino MV, Toxicol Pathol 2004 Jan-Feb;32(1):58-63
Intestine - Small Intestine - Proximal tumor	Intestine - Small Intestine - Proximal	pioglitazone		100			References: Pino MV, Toxicol Pathol 2004 Jan-Feb;32(1):58-63
Intestine - Small Intestine - Proximal tumor	Intestine - Small Intestine - Proximal	rosiglitazone		100			References: Pino MV, Toxicol Pathol 2004 Jan-Feb;32(1):58-63
Intestine - Small Intestine - Proximal tumor	Intestine - Small Intestine - Proximal	aspirin (acetylsalicylic acid) (ASA)			observed		References: Barnes CJ, Gastroenterology 1998 May;114(5):873-7
Intestine - Small Intestine adenoma	Intestine - Small Intestine		observed - 100	very high - 100	observed - 100	observed - 94.74	References: Andrijes R, Proc Natl Acad Sci U S A 2021 Sep 28;118(39): ⋅ Chen Q, Life Sci Alliance 2021 Mar;4(3): ⋅ Paulsen JE, Carcinogenesis 1997 Oct;18(10):1905-10 ⋅ Qi C, Int J Biol Sci 2015;11(6):679-87 ⋅ Shattuck-Brandt RL, Mol Carcinog 1999 Mar;24(3):177-87 ⋅ Steffensen IL, Carcinogenesis 1997 May;18(5):1049-54 ⋅ Weyant MJ, Cancer Res 2001 Mar 15;61(6):2547-51 ⋅ Wilson CL, Proc Natl Acad Sci U S A 1997 Feb 18;94(4):1402-7 ⋅ Woo DK, Am J Pathol 2012 Jan;180(1):24-31 ⋅ Xie G, JCI Insight 2022 Feb 22;7(4):e150894 ⋅ Zheng W, Int J Cancer 2012 Jan 1;130(1):10-9 2 pathology image(s)
Intestine - Small Intestine adenoma	Intestine - Small Intestine	2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)	100	100			References: Steffensen IL, Carcinogenesis 1997 May;18(5):1049-54
Intestine - Small Intestine adenoma	Intestine - Small Intestine	fish oil	very high	very high			References: Paulsen JE, Carcinogenesis 1997 Oct;18(10):1905-10
Intestine - Small Intestine adenoma	Intestine - Small Intestine	ovariectomy	observed				References: Weyant MJ, Cancer Res 2001 Mar 15;61(6):2547-51
Intestine - Small Intestine adenoma	Intestine - Small Intestine	17beta-estradiol (E2) ⋅ ovariectomy	observed				References: Weyant MJ, Cancer Res 2001 Mar 15;61(6):2547-51
Intestine - Small Intestine adenoma - microadenoma	Intestine - Small Intestine					observed	References: Qi C, Int J Biol Sci 2015;11(6):679-87
Intestine - Small Intestine dysplasia	Intestine - Small Intestine				observed		References: Dudley ME, Int J Cancer 1996 Jan 17;65(2):249-53
Intestine - Small Intestine dysplasia - high grade	Intestine - Small Intestine					5.26	References: Andrijes R, Proc Natl Acad Sci U S A 2021 Sep 28;118(39):
Intestine - Small Intestine dysplasia - low grade	Intestine - Small Intestine					94.74	References: Andrijes R, Proc Natl Acad Sci U S A 2021 Sep 28;118(39):
Intestine - Small Intestine lesion	Intestine - Small Intestine					observed	References: Andrijes R, Proc Natl Acad Sci U S A 2021 Sep 28;118(39):
Intestine - Small Intestine lesion - malignant	Intestine - Small Intestine					0	References: Andrijes R, Proc Natl Acad Sci U S A 2021 Sep 28;118(39):
Intestine - Small Intestine polyp	Intestine - Small Intestine				very high	observed - 100	References: Andrijes R, Proc Natl Acad Sci U S A 2021 Sep 28;118(39): ⋅ Dudley ME, Int J Cancer 1996 Jan 17;65(2):249-53 ⋅ Gupta RA, Nat Med 2004 Mar;10(3):245-7 ⋅ Zeineldin M, Oncogene 2012 May 10;31(19):2423-37
Intestine - Small Intestine polyp	Intestine - Small Intestine	GW501516, PPAR-delta agonist				observed	References: Gupta RA, Nat Med 2004 Mar;10(3):245-7
Intestine - Small Intestine tumor	Intestine - Small Intestine	low fiber			100		References: Pierre F, Cancer Res 1997 Jan 15;57(2):225-8
Intestine - Small Intestine tumor	Intestine - Small Intestine	high fiber			100		References: Pierre F, Cancer Res 1997 Jan 15;57(2):225-8
Intestine - Small Intestine tumor	Intestine - Small Intestine		observed	observed	observed - 100	observed - very high	References: Hansen-Petrik MB, Cancer Res 2002 Jan 15;62(2):403-8 ⋅ Ma H, Cell Rep 2020 Jan 21;30(3):793-806.e6 ⋅ Mahmoud NN, Carcinogenesis 1999 Feb;20(2):299-303 ⋅ Qi C, Int J Biol Sci 2015;11(6):679-87 ⋅ Ritland SR, Clin Cancer Res 1999 Apr;5(4):855-63 ⋅ Steffensen IL, Cancer Res 2001 Dec 15;61(24):8689-96 ⋅ Sun X, Mol Cancer 2009;8():73 ⋅ Ton-That H, FEBS Lett 1997 Dec 15;419(2-3):239-43 ⋅ Weyant MJ, Cancer Res 2001 Jan 1;61(1):118-25 ⋅ Williams JL, Biochem Biophys Res Commun 2004 Jan 16;313(3):784-8 ⋅ Xie G, JCI Insight 2022 Feb 22;7(4):e150894 ⋅ Ziegler CC, J Nutr 2004 Jan;134(1):5-10
Intestine - Small Intestine tumor	Intestine - Small Intestine	chenodeoxycholate (chenodeoxycholic acid)	observed				References: Mahmoud NN, Carcinogenesis 1999 Feb;20(2):299-303
Intestine - Small Intestine tumor	Intestine - Small Intestine	sulfasalazine (SASP)			observed		References: Ritland SR, Clin Cancer Res 1999 Apr;5(4):855-63
Intestine - Small Intestine tumor	Intestine - Small Intestine	Pentasa			observed		References: Ritland SR, Clin Cancer Res 1999 Apr;5(4):855-63
Intestine - Small Intestine tumor	Intestine - Small Intestine	5-aminosalicylic acid, free acid (5-ASA)			observed		References: Ritland SR, Clin Cancer Res 1999 Apr;5(4):855-63
Intestine - Small Intestine tumor	Intestine - Small Intestine	(+)-catechin	observed				References: Weyant MJ, Cancer Res 2001 Jan 1;61(1):118-25
Intestine - Small Intestine tumor	Intestine - Small Intestine	piroxicam		observed			References: Hansen-Petrik MB, Cancer Res 2002 Jan 15;62(2):403-8
Intestine - Small Intestine tumor	Intestine - Small Intestine	16,16-dimethyl-prostaglandin E2 (16,16dmPGE2) ⋅ 17-phenyl-trinor-prostaglandin E2		observed			References: Hansen-Petrik MB, Cancer Res 2002 Jan 15;62(2):403-8
Intestine - Small Intestine tumor	Intestine - Small Intestine	16,16-dimethyl-prostaglandin E2 (16,16dmPGE2) ⋅ piroxicam ⋅ 17-phenyl-trinor-prostaglandin E2		observed			References: Hansen-Petrik MB, Cancer Res 2002 Jan 15;62(2):403-8
Intestine - Small Intestine tumor	Intestine - Small Intestine	anti-prostaglandin E₂ (PGE₂monoclonal antibody 2B5)		observed			References: Hansen-Petrik MB, Cancer Res 2002 Jan 15;62(2):403-8
Intestine - Small Intestine tumor	Intestine - Small Intestine	17-phenyl-trinor-prostaglandin E2		observed			References: Hansen-Petrik MB, Cancer Res 2002 Jan 15;62(2):403-8
Intestine - Small Intestine tumor	Intestine - Small Intestine	piroxicam ⋅ 17-phenyl-trinor-prostaglandin E2		observed			References: Hansen-Petrik MB, Cancer Res 2002 Jan 15;62(2):403-8
Intestine - Small Intestine tumor	Intestine - Small Intestine	sulindac		observed			References: Hansen-Petrik MB, Cancer Res 2002 Jan 15;62(2):403-8
Intestine - Small Intestine tumor	Intestine - Small Intestine	16,16-dimethyl-prostaglandin E2 (16,16dmPGE2) ⋅ sulindac ⋅ 17-phenyl-trinor-prostaglandin E2		observed			References: Hansen-Petrik MB, Cancer Res 2002 Jan 15;62(2):403-8
Intestine - Small Intestine tumor	Intestine - Small Intestine	2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)			observed - 100		References: Steffensen IL, Cancer Res 2001 Dec 15;61(24):8689-96
Intestine - Small Intestine tumor	Intestine - Small Intestine	resveratrol		observed			References: Ziegler CC, J Nutr 2004 Jan;134(1):5-10
Intestine - Small Intestine tumor	Intestine - Small Intestine	2-(acetyloxy)benzoic acid 4-(nitrooxy methyl)phenyl ester) (NO-ASA)	90				References: Williams JL, Biochem Biophys Res Commun 2004 Jan 16;313(3):784-8
Intestine adenocarcinoma	Intestine					observed	References: Sun X, Mol Cancer 2009;8():73
Intestine adenoma	Intestine	high saturated fat	very high				References: Wechter WJ, Cancer Res 1997 Oct 1;57(19):4316-24
Intestine adenoma	Intestine	low saturated fat	very high				References: Wechter WJ, Cancer Res 1997 Oct 1;57(19):4316-24
Intestine adenoma	Intestine	high saturated fat ⋅ R-flurbiprofen (R-FB) (E-7869)	very high				References: Wechter WJ, Cancer Res 1997 Oct 1;57(19):4316-24
Intestine adenoma	Intestine	low saturated fat ⋅ R-flurbiprofen (R-FB) (E-7869)	very high				References: Wechter WJ, Cancer Res 1997 Oct 1;57(19):4316-24
Intestine adenoma	Intestine		0 - 100	observed	observed	observed	References: Boolbol SK, Cancer Res 1996 Jun 1;56(11):2556-60 ⋅ Chen Q, Life Sci Alliance 2021 Mar;4(3): ⋅ Goss KJ, Int J Cancer 1998 Nov 23;78(5):629-35 ⋅ Guillen-Ahlers H, Carcinogenesis 2008 Jul;29(7):1421-7 ⋅ Gutierrez LS, Carcinogenesis 2003 Feb;24(2):199-207 ⋅ He XY, Cell Rep 2015 Nov 3;13(5):888-97 ⋅ Heuberger J, Life Sci Alliance 2019 Feb;2(1):e201800173 ⋅ Mahmoud NN, Carcinogenesis 1998 Jan;19(1):87-91 ⋅ Mahmoud NN, Carcinogenesis 2000 May;21(5):921-7 ⋅ Maywald RL, Proc Natl Acad Sci U S A 2015 May 12;112(19):E2487-96 ⋅ Nakatsugi S, Jpn J Cancer Res 1997 Dec;88(12):1117-20 ⋅ Ritland SR, Cancer Res 2000 Sep 1;60(17):4678-81 ⋅ Schmelz EM, Cancer Res 2001 Sep 15;61(18):6723-9 ⋅ Steinbrecher KA, Biochem Biophys Res Commun 2000 Jun 24;273(1):225-30 ⋅ Thompson JA, Int J Cancer 1997 Jul 3;72(1):197-202 ⋅ Wagenaar-Miller RA, Br J Cancer 2003 May 6;88(9):1445-52 ⋅ Weyant MJ, Cancer Res 2001 Jan 1;61(1):118-25 ⋅ Weyant MJ, Cancer Res 2001 Mar 15;61(6):2547-51 ⋅ Yamada T, Cancer Res 2003 Mar 1;63(5):895-901 ⋅ Zheng W, Int J Cancer 2012 Jan 1;130(1):10-9
Intestine adenoma	Intestine	sulindac sulfide	30				References: Mahmoud NN, Carcinogenesis 1998 Jan;19(1):87-91
Intestine adenoma	Intestine	sulindac sulfone	100				References: Mahmoud NN, Carcinogenesis 1998 Jan;19(1):87-91
Intestine adenoma	Intestine	caffeic acid phenethyl ester (CAPE)	very high				References: Mahmoud NN, Carcinogenesis 2000 May;21(5):921-7
Intestine adenoma	Intestine	curcumin	very high				References: Mahmoud NN, Carcinogenesis 2000 May;21(5):921-7
Intestine adenoma	Intestine	quercetin	very high				References: Mahmoud NN, Carcinogenesis 2000 May;21(5):921-7
Intestine adenoma	Intestine	rutin	very high				References: Mahmoud NN, Carcinogenesis 2000 May;21(5):921-7
Intestine adenoma	Intestine	N-[4-(3-chloro-4-fluoro-phenylamino)-quinazolin-6-yl]acrylamide (CFPQA)			observed		References: Ritland SR, Cancer Res 2000 Sep 1;60(17):4678-81
Intestine adenoma	Intestine	(+)-catechin	observed				References: Weyant MJ, Cancer Res 2001 Jan 1;61(1):118-25
Intestine adenoma	Intestine	ceramide (N-palmitoylsphingosine)		observed			References: Schmelz EM, Cancer Res 2001 Sep 15;61(18):6723-9
Intestine adenoma	Intestine	sphingolipid mix		observed			References: Schmelz EM, Cancer Res 2001 Sep 15;61(18):6723-9
Intestine adenoma	Intestine	sphingolipid mix ⋅ ceramide (N-palmitoylsphingosine)		observed			References: Schmelz EM, Cancer Res 2001 Sep 15;61(18):6723-9
Intestine adenoma	Intestine	piroxicam			observed		References: Ritland SR, Cancer Res 2000 Sep 1;60(17):4678-81
Intestine adenoma	Intestine	ovariectomy	observed				References: Weyant MJ, Cancer Res 2001 Mar 15;61(6):2547-51
Intestine adenoma	Intestine	17beta-estradiol (E2) ⋅ ovariectomy	observed				References: Weyant MJ, Cancer Res 2001 Mar 15;61(6):2547-51
Intestine adenoma	Intestine	A-177430, MMP inhibitor				observed	References: Wagenaar-Miller RA, Br J Cancer 2003 May 6;88(9):1445-52
Intestine adenoma	Intestine	A-285969, Cox-2 inhibitor				observed	References: Wagenaar-Miller RA, Br J Cancer 2003 May 6;88(9):1445-52
Intestine adenoma	Intestine	sulindac		observed		observed	References: Guillen-Ahlers H, Carcinogenesis 2008 Jul;29(7):1421-7 ⋅ Wagenaar-Miller RA, Br J Cancer 2003 May 6;88(9):1445-52
Intestine adenoma	Intestine	A-177430, MMP inhibitor ⋅ A-285969, Cox-2 inhibitor				observed	References: Wagenaar-Miller RA, Br J Cancer 2003 May 6;88(9):1445-52
Intestine adenoma	Intestine	nimesulide (4-nitro-2-phenoxymethanesulfonanilide)	observed				References: Nakatsugi S, Jpn J Cancer Res 1997 Dec;88(12):1117-20
Intestine adenoma	Intestine	batimastat (BB-94)				observed	References: Goss KJ, Int J Cancer 1998 Nov 23;78(5):629-35
Intestine adenoma	Intestine	low saturated fat ⋅ S-flurbiprofen (S-FB)	very high				References: Wechter WJ, Cancer Res 1997 Oct 1;57(19):4316-24
Intestine lesion	Intestine					observed	References: Andrijes R, Proc Natl Acad Sci U S A 2021 Sep 28;118(39):
Intestine polyp	Intestine	uroguanylin ⋅ polyethylene glycol		observed			References: Shailubhai K, Cancer Res 2000 Sep 15;60(18):5151-7
Intestine polyp	Intestine	polyethylene glycol		observed			References: Shailubhai K, Cancer Res 2000 Sep 15;60(18):5151-7
Intestine polyp	Intestine		observed			observed - 100	References: Andrijes R, Proc Natl Acad Sci U S A 2021 Sep 28;118(39): ⋅ He XY, Cell Rep 2015 Nov 3;13(5):888-97 ⋅ Heuberger J, Life Sci Alliance 2019 Feb;2(1):e201800173 ⋅ Maywald RL, Proc Natl Acad Sci U S A 2015 May 12;112(19):E2487-96 ⋅ Mutoh M, Cancer Res 2002 Jan 1;62(1):28-32 ⋅ Qi C, Int J Biol Sci 2015;11(6):679-87 ⋅ Wang X, Oncogene 2017 Aug 31;36(35):4987-4996
Intestine polyp	Intestine	2-[2-{2-(1-naphthyl)propanoylamino}phenyl]methylbenzoic acid (ONO-AE2-227)	observed				References: Mutoh M, Cancer Res 2002 Jan 1;62(1):28-32
Intestine polyp	Intestine	anti-IL1RL1 (mu-IgG1-FC?anti-muST2, Amgen)				observed	References: Maywald RL, Proc Natl Acad Sci U S A 2015 May 12;112(19):E2487-96
Intestine polyp	Intestine	anti-IgG (4D2-mu-IgG1?anti-huAGP3-Pb, Amgen)				observed	References: Maywald RL, Proc Natl Acad Sci U S A 2015 May 12;112(19):E2487-96
Intestine polyp - adenomatous	Intestine					observed	References: Maywald RL, Proc Natl Acad Sci U S A 2015 May 12;112(19):E2487-96 ⋅ Zheng W, Int J Cancer 2012 Jan 1;130(1):10-9
Intestine tumor	Intestine		observed - 100	observed	observed	observed - 100	References: Andrijes R, Proc Natl Acad Sci U S A 2021 Sep 28;118(39): ⋅ Barnes CJ, Gastroenterology 1998 May;114(5):873-7 ⋅ Boolbol SK, Cancer Res 1996 Jun 1;56(11):2556-60 ⋅ Dudley ME, Int J Cancer 1996 Jan 17;65(2):249-53 ⋅ Heuberger J, Life Sci Alliance 2019 Feb;2(1):e201800173 ⋅ Lefebvre AM, Nat Med 1998 Sep;4(9):1053-7 ⋅ Maywald RL, Proc Natl Acad Sci U S A 2015 May 12;112(19):E2487-96 ⋅ Moser AR, Cancer Res 2001 Apr 15;61(8):3480-5 ⋅ Oster H, Cancer Res 2006 Jul 15;66(14):6955-63 ⋅ Qi C, Int J Biol Sci 2015;11(6):679-87 ⋅ Ritland SR, Clin Cancer Res 1999 Apr;5(4):855-63 ⋅ Wang X, Oncogene 2017 Aug 31;36(35):4987-4996 ⋅ Wilson CL, Proc Natl Acad Sci U S A 1997 Feb 18;94(4):1402-7 ⋅ Zheng W, Int J Cancer 2012 Jan 1;130(1):10-9
Intestine tumor	Intestine	piroxicam			observed		References: Ritland SR, Clin Cancer Res 1999 Apr;5(4):855-63
Intestine tumor	Intestine	sulindac	10		observed		References: Boolbol SK, Cancer Res 1996 Jun 1;56(11):2556-60 ⋅ Ritland SR, Clin Cancer Res 1999 Apr;5(4):855-63
Intestine tumor	Intestine	5-aminosalicylic acid, free acid (5-ASA)			observed		References: Ritland SR, Clin Cancer Res 1999 Apr;5(4):855-63
Intestine tumor	Intestine	4-aminosalicylic acid, sodium salt (4-ASA)			observed		References: Ritland SR, Clin Cancer Res 1999 Apr;5(4):855-63
Intestine tumor	Intestine	Pentasa			observed		References: Ritland SR, Clin Cancer Res 1999 Apr;5(4):855-63
Intestine tumor	Intestine	sulfasalazine (SASP)			observed		References: Ritland SR, Clin Cancer Res 1999 Apr;5(4):855-63
Intestine tumor	Intestine	BRL-49,653, PPAR gamma ligand		observed			References: Lefebvre AM, Nat Med 1998 Sep;4(9):1053-7
Intestine tumor	Intestine	troglitazone		observed			References: Lefebvre AM, Nat Med 1998 Sep;4(9):1053-7
Intestine tumor	Intestine	aspirin (acetylsalicylic acid) (ASA)			observed		References: Barnes CJ, Gastroenterology 1998 May;114(5):873-7
Intestine tumor	Intestine	anti-IL1RL1 (mu-IgG1-FC?anti-muST2, Amgen)				observed	References: Maywald RL, Proc Natl Acad Sci U S A 2015 May 12;112(19):E2487-96
Intestine tumor	Intestine	anti-IgG (4D2-mu-IgG1?anti-huAGP3-Pb, Amgen)				observed	References: Maywald RL, Proc Natl Acad Sci U S A 2015 May 12;112(19):E2487-96
Intestine tumor	Intestine	tamoxifen (for inducing expression from mutant alleles)				observed	References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23
Intestine tumor - epithelial	Intestine					observed	References: Wang X, Oncogene 2017 Aug 31;36(35):4987-4996
Stomach polyp	Stomach					45.45	References: Zeineldin M, Oncogene 2012 May 10;31(19):2423-37

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