Model DetailsIntestine - Large Intestine - Colon adenoma

Model Name	Intestine - Large Intestine - Colon adenoma
Strain	C57BL/6J-Apc^Min/+
Tumor Inducing Agent(s)	None (spontaneous)
Tumor Synonyms	colon adenoma • colorectal adenoma • high-grade focal dysplasia • colon tumor • benign adenoma • microadenoma • intestinal polyp • colonic adenoma • high-grade focal adenoma
Strain Synonyms	C57BL/6J-APC^Min/+ • C57BL/6J-Apc^Min/J • APC^min/+ • C57BL/6J/Min/+ • C57BL/6J-Apc^Min • Apc^Min • C57BL/6 Apc^Min/+ • C57BL/6J-Min • B6-Apc^Min/Apc⁺ • C57Bl/6J-Min+ • Apc^Min • C57BL/6J-Apc^Min/+ • Min C57BL/6J • C57BL/6J-APC^min/+ • C57BL/6J Min /+ • Apc^Min/+ • Apc+/- • Apc+/- Msh2+/+ • APC^Min/+ • Min • C57BL/6J Apc^Min/+ • C57Bl/6-Min • adenomatous polyposis coli^Min/+ • C57BL/6J-Min/+ • APC^Min/+ • C57BL/6J-Apc^Min • C57BL/6J-Apc^Min/+ • C57BL/6J APC^Min/+ • C57BL/6J Min • B6-Apc^Min • C57Bl/6-Min/+ • C57BL/6-Min • C57BL/6J-Min/+ • Apc^Min/+ • C57BL/6-Min • Apc^Min/+ • C57BL/6J-APC^Min/+ • C57Bl/6J-Min/+ • Min/+ • ApcMin • Apc^Min heterozygous • Min/+ • Apc^Min • C57BL/6J-Apc^Min/+ • C57Bl/6J^Min/+ • Apc^min • multiple intestinal neoplasia • C57BL/6J Apc^Min/+ • Apc^Min/Apc⁺ • C57BL/6J Min/+ • B6 Min/+ • Min • C57BL/6J Min • APC^Min/+ • C57BL/6J-Apc^Min/J • Min/+ C57BL/6J • Apc^Min/+ • APC^Min/+ • C57BL/6J Apc^min • C57BL/6J/-Apc^Min

Organ Affected	Sex	Frequency	Age Of Detection	Additional Information Expand all Collapse all	Reference
Intestine - Large Intestine - Colon	Unspecified	observed		Notes Reproductive Status: reproductive status not specified Pathology Reports	Wilson CL, Proc Natl Acad Sci U S A 1997 Feb 18;94(4):1402-7
Intestine - Large Intestine - Colon	Unspecified	observed		Notes Reproductive Status: reproductive status not specified Pathology Reports	Shattuck-Brandt RL, Mol Carcinog 1999 Mar;24(3):177-87
Intestine - Large Intestine - Colon	Unspecified	observed	15 weeks	Notes Reproductive Status: reproductive status not specified Pathology Reports	Bjerknes M, Am J Pathol 1999 Jun;154(6):1831-4
Intestine - Large Intestine - Colon	Male	observed	100 days	Treatment Notes Notes Reproductive Status: reproductive status not specified	Schmelz EM, Cancer Res 2001 Sep 15;61(18):6723-9
Intestine - Large Intestine - Colon	Mixed Population	observed	99-111 days	Treatment Notes Notes Reproductive Status: reproductive status not specified	Ritland SR, Cancer Res 2000 Sep 1;60(17):4678-81
Intestine - Large Intestine - Colon	Male	91.67% (11 of 12 mice)	18-20 weeks	Notes Reproductive Status: reproductive status not specified	Woo DK, Am J Pathol 2012 Jan;180(1):24-31
Intestine - Large Intestine - Colon	Male	100% (11 of 11 mice)	20 weeks	Notes Reproductive Status: reproductive status not specified	Woo DK, Am J Pathol 2012 Jan;180(1):24-31
Intestine - Large Intestine - Colon	Mixed Population	observed	20 weeks	Notes Reproductive Status: reproductive status not specified	Chen Q, Life Sci Alliance 2021 Mar;4(3):
Intestine - Large Intestine - Colon	Mixed Population	100% (14 of 14 mice)	20 weeks	Notes Reproductive Status: reproductive status not specified	Chen Q, Life Sci Alliance 2021 Mar;4(3):
Intestine - Large Intestine - Colon	Mixed Population	100% (5 of 5 mice)	20 weeks	Notes Reproductive Status: reproductive status not specified	Chen Q, Life Sci Alliance 2021 Mar;4(3):
Intestine - Large Intestine - Colon	Unspecified	0% (0 of 19 mice)		Notes Reproductive Status: reproductive status not specified	Andrijes R, Proc Natl Acad Sci U S A 2021 Sep 28;118(39):
Intestine - Large Intestine - Colon	Unspecified	observed	15 weeks	Notes Reproductive Status: reproductive status not specified	Xie G, JCI Insight 2022 Feb 22;7(4):e150894