Model DetailsProstate gland prostatic intraepithelial neoplasia - high grade (HGPIN)
Model Name |
Prostate gland prostatic intraepithelial neoplasia - high grade (HGPIN) | Strain |
B6;129S-Nkx3-1tm1Mms/? Ptentm1Rps/+ |
Tumor Inducing Agent(s) |
None (spontaneous) |
Tumor Synonyms |
high-grade prostatic intraepithelial neoplasia • cancer • HGPIN |
Strain Synonym |
Nkx3.1+/- or -/-; Pten+/-; p27+/+ |
| Organ Affected | Sex | Frequency | Age Of Detection | Additional Information Expand all Collapse all | Reference |
|---|---|---|---|---|---|
| Prostate gland | Male |
33% (6 of 18 mice) |
≤6 months |
|
Gao H, Proc Natl Acad Sci U S A 2004 Dec 7;101(49):17204-9 |
| Prostate gland | Male |
73% (33 of 45 mice) |
>6 months |
|
Gao H, Proc Natl Acad Sci U S A 2004 Dec 7;101(49):17204-9 |