Model DetailsLiver adenoma
Model Name |
Liver adenoma | Strain |
B6.129S7-Trp53tm1Brd/+ |
Tumor Inducing Agent(s) |
Chemical/Drug : 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) |
Tumor Synonyms |
Liver adenoma • Liver tumor |
Strain Synonyms |
p53+/- Deficient • p53+/- • C57Bl/6Tac-[KO]Trp53N5-T • C57bl/6N12-Trp53 heterozygous (+/-) • p53-deficient • B6.129-Trp53tm1Brd/+ • p53(+/-) • C57BL/6TacfBR-[KO] p53 N5 heterozygous mice • p53+/- • p53+/- • heterozygous p53 knockout |
| Organ Affected | Sex | Frequency | Age Of Detection | Additional Information Expand all Collapse all | Reference |
|---|---|---|---|---|---|
| Liver | Unspecified |
13.3% (2 of 15 mice) |
7 months |
|
Dass SB, Cancer Lett 1999 Aug 23;143(1):81-5 |
| Liver | Unspecified |
5.9% (1 of 17 mice) |
7 months |
|
Dass SB, Cancer Lett 1999 Aug 23;143(1):81-5 |