Model DetailsLiver preneoplastic lesion

Model Name

 Liver preneoplastic lesion

Strain
B6.129S7-Trp53tm1Brd/+

Tumor Inducing Agent(s)

 Chemical/Drug : diethylnitrosamine (DEN)

Tumor Synonyms

 preneoplastic liver lesions  •  focal hepatic lesions  •  focal lesions

Strain Synonyms

 p53+/- Deficient  •  p53+/-  •  C57Bl/6Tac-[KO]Trp53N5-T  •  C57bl/6N12-Trp53 heterozygous (+/-)  •  p53-deficient  •  B6.129-Trp53tm1Brd/+  •  p53(+/-)  •  C57BL/6TacfBR-[KO] p53 N5 heterozygous mice  •  p53+/-  •  p53+/-  •  heterozygous p53 knockout
Organ Affected Sex Frequency Age Of Detection Additional Information Expand all Collapse all Reference
Liver Female

observed

 22-27 weeks
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

 Finnberg N, Cancer Lett 2004 Apr 30;207(2):149-55