Pathology Image Search Results

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Contains
Antibody
anti-alpha smooth muscle actin (A2547)
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5
5 (of 15) pathology reports displayed, including 18 images.
MTB ID Tumor Name Organ(s) Affected Treatment Type Agents Strain Name Strain Sex Reproductive Status Tumor Frequency Age at Necropsy Description Reference
MTB:27648 Intestine   normal tissue (control) Intestine None (spontaneous)
C57BL/6J
 Unspecified reproductive status not specified not applicable unknown Intestine - Smooth muscle - normal tissue. J:94310
Image Caption:Colon - Normal tissue. There is intense cytoplasmic labelling for alpha smooth muscle actin of smooth muscle fibers of the muscularis mucosae and of the wall of the colon (antibody diluted at 1:6,000, tissue fixed in Bouin's solution).
1102
Image ID:1102
Source of Image:Mikaelian I
Pathologist:Mikaelian I
Method / Stain:IHC for alpha smooth muscle actin
Image Caption:Intestine - Smooth muscle - Normal tissue. There is intense labelling of smooth muscle fibers located in intestinal villi and in the wall of the intestine. There is mild interstitial background labelling. The tissue was fixed in Fekete's solution and labeled with an antibody diluted at 1:40,000.
231
Image ID:231
Source of Image:Mikaelian I
Pathologist:Mikaelian I
Method / Stain:IHC for alpha smooth muscle actin
Image Caption:Intestine - Smooth muscle - Normal tissue. There is strong labeling of smooth muscle fibers located in intestinal villi and in the wall of the intestine. There is no interstitial background labelling. The tissue was fixed in Bouin's fixative and labeled with an antibody diluted at 1:40,000.
233
Image ID:233
Source of Image:Mikaelian I
Pathologist:Mikaelian I
Method / Stain:IHC for alpha smooth muscle actin
Image Caption:Intestine - Smooth muscle - Normal tissue. There is intense labeling of smooth muscle fibers located in intestinal villi and in the wall of the intestine. There is no background labeling. The tissue was fixed in Zinc buffer and labelled with an antibody diluted at 1:40,000.
235
Image ID:235
Source of Image:Mikaelian I
Pathologist:Mikaelian I
Method / Stain:IHC for alpha smooth muscle actin
Image Caption:Intestine - Smooth muscle - Normal tissue. There is strong labeling of smooth muscle fibers located in intestinal villi and in the wall of the intestine. There is moderate interstitial background labeling. The tissue was fixed in 10% neutral buffered formalin and labeled with an antibody diluted at 1:40,000.
237
Image ID:237
Source of Image:Mikaelian I
Pathologist:Mikaelian I
Method / Stain:IHC for alpha smooth muscle actin
Image Caption:Intestine - Smooth muscle - Normal tissue. There is strong labeling of smooth muscle fibers located in intestinal villi and in the wall of the intestine. There is mild interstitial background labeling. The tissue was fixed in 4% paraformaldehyde and labeled with an antibody diluted at 1:40,000.
239
Image ID:239
Source of Image:Mikaelian I
Pathologist:Mikaelian I
Method / Stain:IHC for alpha smooth muscle actin
MTB ID Tumor Name Organ(s) Affected Treatment Type Agents Strain Name Strain Sex Reproductive Status Tumor Frequency Age at Necropsy Description Reference
MTB:18035 Mammary gland   adenocarcinoma Mammary gland None (spontaneous)
C3H/HeJ
 Female reproductive status not specified observed 210 days Mammary gland, adenocarcinoma. J:94310
Image Caption:Mammary gland, adenocarcinoma.
Cells located at the periphery of neoplastic trabeculae and lobules show intense immunolabeling for alpha smooth muscle actin, which indicates myoepithelial differentiation.
209
Image ID:209
Source of Image:Mikaelian I
Pathologist:Mikaelian I
Method / Stain:IHC for alpha smooth muscle actin
MTB ID Tumor Name Organ(s) Affected Treatment Type Agents Strain Name Strain Sex Reproductive Status Tumor Frequency Age at Necropsy Description Reference
MTB:18036 Mammary gland   adenocarcinoma Mammary gland None (spontaneous)
C3H/HeJ
 Female reproductive status not specified observed 186 days Mammary gland, adenocarcinoma. J:94310
Image Caption:Mammary gland, adenocarcinoma. A continuous row of neoplastic cells, located at the periphery of neoplastic lobules, labels for alpha smooth muscle actin.
222
Image ID:222
Source of Image:Mikaelian I
Pathologist:Mikaelian I
Method / Stain:IHC for alpha smooth muscle actin
Image Caption:Mammary gland, adenocarcinoma. Smooth muscle fibers of blood vessels within the neoplasm label intensely for alpha smooth muscle actin.
220
Image ID:220
Source of Image:Mikaelian I
Pathologist:Mikaelian I
Method / Stain:IHC for alpha smooth muscle actin
Image Caption:Mammary gland, adenocarcinoma. Neoplastic cells labeling for alpha smooth muscle actin form a continuous row at the periphery of neoplastic lobules in this area with a comedo pattern. In addition, a moderate number of neoplastic cells randomly distributed in neoplastic lobules moderately label for alpha smooth muscle actin. A moderate number of myofibroblasts scattered in the stroma of the tumor and smooth muscle fibers of the wall of blood vessels also label for alpha smooth muscle actin.
221
Image ID:221
Source of Image:Mikaelian I
Pathologist:Mikaelian I
Method / Stain:IHC for alpha smooth muscle actin
MTB ID Tumor Name Organ(s) Affected Treatment Type Agents Strain Name Strain Sex Reproductive Status Tumor Frequency Age at Necropsy Description Reference
MTB:18037 Mammary gland   adenocarcinoma Lung None (spontaneous)
C3H/HeJ
 Female reproductive status not specified observed 186 days Lung: Mammary adenocarcinoma, metastatic to the lung. J:94310
Image Caption:Lung: mammary adenocarcinoma, metastatic to the lung. This figure represents a low magnification image of a mammary adenocarcinoma metastatic to the lung and immunolabeled for alpha smooth muscle actin. A few scattered neoplastic cells and smooth muscle fibers of the wall of blood vessels of the stroma strongly label for smooth muscle actin. Labeling of neoplastic cells indicates myoepithelial differentiation.
211
Image ID:211
Source of Image:Mikaelian I
Pathologist:Mikaelian I
Method / Stain:IHC for alpha smooth muscle actin
Image Caption:Mammary adenocarcinoma, metastatic to the lung, tubular area. Labeling for alpha smooth muscle actin is restricted to basal cells in this area of tubular differentiation. This feature indicates myoepithelial differentiation.
212
Image ID:212
Source of Image:Mikaelian I
Pathologist:Mikaelian I
Method / Stain:IHC for alpha smooth muscle actin
Image Caption:Mammary adenocarcinoma, metastatic to the lung. A neoplastic embolus originating from a mammary tumor is present in an ectatic pulmonary artery. Scattered neoplastic cells within the embolus intensely label for alpha smooth muscle actin, which indicates myoepithelial differentiation. There is also intense labeling of smooth muscle fibers of the wall of the artery.
210
Image ID:210
Source of Image:Mikaelian I
Pathologist:Mikaelian I
Method / Stain:IHC for alpha smooth muscle actin
MTB ID Tumor Name Organ(s) Affected Treatment Type Agents Strain Name Strain Sex Reproductive Status Tumor Frequency Age at Necropsy Description Reference
MTB:18038 Mammary gland   adenocarcinoma Mammary gland None (spontaneous)
C3H/HeJ
 Female reproductive status not specified observed 173 days Mammary gland, adenocarcinoma. J:94310
Image Caption:Mammary gland, adenocarcinoma. A continuous row of neoplastic cells at the periphery of a neoplastic lobule label intensely for alpha smooth muscle actin, which indicates myoepithelial differentiation. Scattered neoplastic cells throughout the lobule and smooth muscle fibers in the wall of a small vein also label strongly for alpha smooth muscle actin.
217
Image ID:217
Source of Image:Mikaelian I
Pathologist:Mikaelian I
Method / Stain:IHC for alpha smooth muscle actin
Image Caption:Mammary gland, adenocarcinoma. Neoplastic cells at the periphery of large lobules in an area with a comedo pattern strongly label for alpha smooth muscle actin. A few neoplastic cells scattered throughout neoplastic lobules show moderate labeling.
219
Image ID:219
Source of Image:Mikaelian I
Pathologist:Mikaelian I
Method / Stain:IHC for alpha smooth muscle actin
Image Caption:Mammary gland, adenocarcinoma. Neoplastic cells at the periphery of neoplastic lobules intensely label for alpha smooth muscle actin, which indicates myoepithelial differentiation. This picture is taken from an area where the neoplasm had a solid to comedo-type pattern.
215
Image ID:215
Source of Image:Mikaelian I
Pathologist:Mikaelian I
Method / Stain:IHC for alpha smooth muscle actin
Image Caption:Mammary gland, adenocarcinoma. Neoplastic cells located at the periphery of tubular structures intensely label for smooth muscle actin in this area with a tubular pattern. Alpha smooth muscle actin expression is an indication of smooth muscle differentiation.
216
Image ID:216
Source of Image:Mikaelian I
Pathologist:Mikaelian I
Method / Stain:IHC for alpha smooth muscle actin
Image Caption:Mammary gland, adenocarcinoma. This figure represent an area of transition between an acinar pattern (lower left) and a solid pattern (upper right). Neoplastic cells at the periphery of the acini and thick trabeculae label strongly for alpha smooth muscle actin, which indicates myoepithelial differentiation.
218
Image ID:218
Source of Image:Mikaelian I
Pathologist:Mikaelian I
Method / Stain:IHC for alpha smooth muscle actin