Reference SummaryFlaks A, Eur J Cancer 1968 Dec;4(6):579-85

Title

 The susceptibility of various strains of neonatal mice to the carcinogenic effects of 9,10-dimethyl-1,2-benzanthracene.

Authors

 Flaks A

Journal

 Eur J Cancer

Volume

 4

Issue

 6

Year

 1968

Pages

 579-85

Abstract

Links

 J:23487 – MGI References
5717955 – National Library of Medicine/PubMed

Models
Strain Model Name Treatment Agent(s) Organ Affected Frequency Model Details
A/Flaks Connective tissue - Fibroblast fibrosarcoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Connective tissue - Fibroblast

7.7 - 9.1
C57BL Connective tissue - Fibroblast fibrosarcoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Connective tissue - Fibroblast

3.8 - 4.5
(A/Flaks x C57BL)F1 Connective tissue - Fibroblast fibrosarcoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Connective tissue - Fibroblast

3.8 - 9.1
(C57BL x A/Flaks)F1 Connective tissue - Fibroblast fibrosarcoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Connective tissue - Fibroblast

8 - 8.3
CBA Connective tissue - Fibroblast fibrosarcoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Connective tissue - Fibroblast

0 - 4.8
C3H Connective tissue - Fibroblast fibrosarcoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Connective tissue - Fibroblast

23 - 33
(CBA x C3H)F1 Connective tissue - Fibroblast fibrosarcoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Connective tissue - Fibroblast

4.2 - 7.7
(C3H x CBA)F1 Connective tissue - Fibroblast fibrosarcoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Connective tissue - Fibroblast

8 - 27
BALB/c Connective tissue - Fibroblast fibrosarcoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Connective tissue - Fibroblast

7.7 - 17
IF Connective tissue - Fibroblast fibrosarcoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Connective tissue - Fibroblast

4.8 - 8.3
(C3H x CBA)F1 Intestine carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Intestine

4
(CBA x C3H)F1 Kidney adenoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Kidney

3.8
(A/Flaks x C57BL)F1 Leukocyte - Lymphocyte lymphoma - small lymphocytic
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Leukocyte - Lymphocyte

4.5
A/Flaks Leukocyte leukemia Leukocyte

0
C57BL Leukocyte leukemia Leukocyte

0
(A/Flaks x C57BL)F1 Leukocyte leukemia Leukocyte

0
(C57BL x A/Flaks)F1 Leukocyte leukemia Leukocyte

0
CBA Leukocyte leukemia Leukocyte

0
C3H Leukocyte leukemia Leukocyte

0
(CBA x C3H)F1 Leukocyte leukemia Leukocyte

0
(C3H x CBA)F1 Leukocyte leukemia Leukocyte

0
BALB/c Leukocyte leukemia Leukocyte

0 - 14
IF Leukocyte leukemia Leukocyte

0
A/Flaks Leukocyte leukemia
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Leukocyte

0
C57BL Leukocyte leukemia
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Leukocyte

0 - 15
(A/Flaks x C57BL)F1 Leukocyte leukemia
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Leukocyte

38 - 59
(C57BL x A/Flaks)F1 Leukocyte leukemia
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Leukocyte

42 - 60
CBA Leukocyte leukemia
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Leukocyte

19 - 48
C3H Leukocyte leukemia
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Leukocyte

21 - 32
(CBA x C3H)F1 Leukocyte leukemia
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Leukocyte

23 - 37.5
(C3H x CBA)F1 Leukocyte leukemia
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Leukocyte

24 - 45
BALB/c Leukocyte leukemia
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Leukocyte

35 - 52
IF Leukocyte leukemia
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Leukocyte

12.5 - 29
C3H Liver hepatoma Liver

0 - 27
A/Flaks Liver hepatoma Liver

0
C57BL Liver hepatoma Liver

0
(A/Flaks x C57BL)F1 Liver hepatoma Liver

0
(C57BL x A/Flaks)F1 Liver hepatoma Liver

0
CBA Liver hepatoma Liver

3.7 - 15
(CBA x C3H)F1 Liver hepatoma Liver

0 - 24
(C3H x CBA)F1 Liver hepatoma Liver

8.8 - 19
BALB/c Liver hepatoma Liver

0
IF Liver hepatoma Liver

0
A/Flaks Liver hepatoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Liver

4.5 - 12
C57BL Liver hepatoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Liver

3.8 - 18
(A/Flaks x C57BL)F1 Liver hepatoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Liver

3.8 - 4.5
(C57BL x A/Flaks)F1 Liver hepatoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Liver

4.2 - 24
CBA Liver hepatoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Liver

36 - 52
C3H Liver hepatoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Liver

33 - 77
(CBA x C3H)F1 Liver hepatoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Liver

58 - 69
(C3H x CBA)F1 Liver hepatoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Liver

36 - 41
BALB/c Liver hepatoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Liver

0 - 12
IF Liver hepatoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Liver

8.3 - 14
A/Flaks Liver hepatoma - malignant
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Liver

0
C57BL Liver hepatoma - malignant
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Liver

0
(A/Flaks x C57BL)F1 Liver hepatoma - malignant
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Liver

0
(C57BL x A/Flaks)F1 Liver hepatoma - malignant
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Liver

0
CBA Liver hepatoma - malignant
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Liver

0 - 24
C3H Liver hepatoma - malignant
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Liver

0 - 4.5
(CBA x C3H)F1 Liver hepatoma - malignant
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Liver

0 - 23
(C3H x CBA)F1 Liver hepatoma - malignant
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Liver

0
BALB/c Liver hepatoma - malignant
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Liver

0
IF Liver hepatoma - malignant
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Liver

0
A/Flaks Lung adenoma Lung

13 - 23
A/Flaks Lung adenoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Lung

100
C57BL Lung adenoma Lung

0
(A/Flaks x C57BL)F1 Lung adenoma Lung

12 - 17
(C57BL x A/Flaks)F1 Lung adenoma Lung

8.8 - 13
CBA Lung adenoma Lung

0
C3H Lung adenoma Lung

0
(CBA x C3H)F1 Lung adenoma Lung

0
(C3H x CBA)F1 Lung adenoma Lung

0
BALB/c Lung adenoma Lung

1.7 - 5.3
IF Lung adenoma Lung

4 - 4.7
C57BL Lung adenoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Lung

0 - 3.8
(A/Flaks x C57BL)F1 Lung adenoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Lung

96 - 100
(C57BL x A/Flaks)F1 Lung adenoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Lung

100
CBA Lung adenoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Lung

64 - 67
C3H Lung adenoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Lung

50 - 64
(CBA x C3H)F1 Lung adenoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Lung

62.5 - 65
(C3H x CBA)F1 Lung adenoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Lung

23 - 56
BALB/c Lung adenoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Lung

92 - 100
IF Lung adenoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Lung

75 - 95
A/Flaks Lung carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Lung

32 - 42
C57BL Lung carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Lung

0
(A/Flaks x C57BL)F1 Lung carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Lung

7.7 - 14
(C57BL x A/Flaks)F1 Lung carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Lung

16 - 29
CBA Lung carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Lung

8 - 14
C3H Lung carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Lung

0 - 4.5
(CBA x C3H)F1 Lung carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Lung

0 - 7.7
(C3H x CBA)F1 Lung carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Lung

4 - 4.5
BALB/c Lung carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Lung

8.7 - 27
IF Lung carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Lung

0 - 4.8
A/Flaks Mammary gland carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Mammary gland

0
C57BL Mammary gland carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Mammary gland

0
(A/Flaks x C57BL)F1 Mammary gland carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Mammary gland

0
(C57BL x A/Flaks)F1 Mammary gland carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Mammary gland

0
CBA Mammary gland carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Mammary gland

0
C3H Mammary gland carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Mammary gland

0
(CBA x C3H)F1 Mammary gland carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Mammary gland

0
(C3H x CBA)F1 Mammary gland carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Mammary gland

8
BALB/c Mammary gland carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Mammary gland

0
IF Mammary gland carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Mammary gland

0
C3H Muscle - Striated - Skeletal rhabdomyosarcoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Muscle - Striated - Skeletal

8.3
BALB/c Muscle - Striated - Skeletal rhabdomyosarcoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Muscle - Striated - Skeletal

3.8
A/Flaks Ovary carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Ovary

3.8
C57BL Ovary carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Ovary

0
(A/Flaks x C57BL)F1 Ovary carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Ovary

7.7
(C57BL x A/Flaks)F1 Ovary carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Ovary

8.3
CBA Ovary carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Ovary

8
C3H Ovary carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Ovary

4.2
(CBA x C3H)F1 Ovary carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Ovary

12.5
(C3H x CBA)F1 Ovary carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Ovary

8
BALB/c Ovary carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Ovary

0
IF Ovary carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Ovary

8.3
BALB/c Salivary gland carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 Salivary gland

3.8
BALB/c (Unspecified organ) squamous cell carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
 (Unspecified organ)

8.7