Strain SummaryC57BL

Strain Name

 C57BL

Strain Type(s)

 inbred

Strain Synonym(s)

 B  •  C57 Bl.  •  C57 black  •  C57 Black

Description

 Substrain not specified.

Strain Links

 • Festing's List of Inbred Strains

Models

85 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Blood vessel hemangioendothelioma Blood vessel 4-o-tolylazo-o-toluidine (2-amino-5-azotoluene)

observed

References: Deringer MK, J Natl Cancer Inst 1956;17(4):533-9

Blood vessel hemangioma Blood vessel

0.4

References: Little CC, Am J Cancer 1939;36(3):431-450

Blood vessel hemangioma - cavernous Blood vessel

0.6

References: Little CC, Am J Cancer 1939;36(3):431-450

Bone osteosarcoma Bone

0.2

References: Little CC, Am J Cancer 1939;36(3):431-450

Bone tumor Bone

1.5

References: Little CC, Am J Cancer 1939;36(3):431-450

CNS - Brain - Undifferentiated cell medulloblastoma CNS - Brain - Undifferentiated cell

observed

References: Murphy ED, 1966;():521-62

CNS - Brain glioma CNS - Brain

observed

References: Murphy ED, 1966;():521-62

Connective tissue - Fibroblast fibrosarcoma Connective tissue - Fibroblast

0.9 - 1.5

0.6

References: Little CC, Am J Cancer 1939;36(3):431-450

Connective tissue - Fibroblast fibrosarcoma Connective tissue - Fibroblast 9,10-dimethyl-1,2-benzanthracene (DMBA)

3.8

4.5

References: Flaks A, Eur J Cancer 1968 Dec;4(6):579-85

Connective tissue - Fibroblast fibrosarcoma Connective tissue - Fibroblast methylcholanthrene (MCA)

observed

References: Festing MFW, Mouse Genome 1996;94(3):523-677

Eye adenocarcinoma - papillary Eye

0.6

References: Little CC, Am J Cancer 1939;36(3):431-450

Intestine - Large Intestine - Rectum carcinoma Intestine - Large Intestine - Rectum

0.8

References: Little CC, Am J Cancer 1939;36(3):431-450

Intestine - Large Intestine - Rectum hyperplasia Intestine - Large Intestine - Rectum

observed

References: Little CC, Am J Cancer 1939;36(3):431-450

Intestine - Small Intestine - Duodenum polyp Intestine - Small Intestine - Duodenum

observed

References: Frith CH, Lab Anim Sci 1983 Jun;33(3):273-86

Intestine polyp - carcinomatous/mucosal Intestine

0.2

References: Little CC, Am J Cancer 1939;36(3):431-450

Intestine tumor Intestine

observed

References: Frith CH, Lab Anim Sci 1983 Jun;33(3):273-86

Kidney carcinoma Kidney

0.6

References: Little CC, Am J Cancer 1939;36(3):431-450

Kidney tumor - benign Kidney toothpaste (control)

0

References: Roe FJ, J Environ Pathol Toxicol 1979 Jan-Feb;2(3):799-819

Kidney tumor - benign Kidney chloroform   ⋅   toothpaste (control)

0

References: Roe FJ, J Environ Pathol Toxicol 1979 Jan-Feb;2(3):799-819

Kidney tumor - malignant Kidney toothpaste (control)

0

References: Roe FJ, J Environ Pathol Toxicol 1979 Jan-Feb;2(3):799-819

Kidney tumor - malignant Kidney chloroform   ⋅   toothpaste (control)

0

References: Roe FJ, J Environ Pathol Toxicol 1979 Jan-Feb;2(3):799-819

Leukocyte - Lymphoblast lymphoblastoma Leukocyte - Lymphoblast

6.5 - 11

13

References: Little CC, Am J Cancer 1939;36(3):431-450

Leukocyte - Lymphocyte leukemia - lymphocytic Leukocyte - Lymphocyte

1.7

References: Staats J, Companion to Mouse News Lett No. 33 1965;():

Leukocyte - Lymphocyte lymphoma - small lymphocytic Leukocyte - Lymphocyte

observed

References: Staats J, Companion to Mouse News Lett No. 21 1959;():

Leukocyte - Lymphocyte reticulum cell neoplasm, type A Leukocyte - Lymphocyte

15.0 - 20.0

References: Murphy ED, 1966;():521-62

Leukocyte leukemia Leukocyte

0

0

References: Flaks A, Eur J Cancer 1968 Dec;4(6):579-85

Leukocyte leukemia Leukocyte 9,10-dimethyl-1,2-benzanthracene (DMBA)

15

0

References: Flaks A, Eur J Cancer 1968 Dec;4(6):579-85

Leukocyte lymphoma Leukocyte X-radiation

83

85

References: Kaplan HS, J Natl Cancer Inst 1955;15(4):975-9

Leukocyte lymphoma Leukocyte radiation - unspecified type

90.0 - 100.0

References: Staats J, Cancer Res 1985 Mar;45(3):945-77

Leukocyte lymphoma Leukocyte toothpaste (control)

19.23

References: Roe FJ, J Environ Pathol Toxicol 1979 Jan-Feb;2(3):799-819

Leukocyte lymphoma Leukocyte chloroform   ⋅   toothpaste (control)

13.46

References: Roe FJ, J Environ Pathol Toxicol 1979 Jan-Feb;2(3):799-819

Leukocyte lymphoma - lymphosarcoma Leukocyte

observed

References: International Nomenclature Committee, Cancer Res 1952 Aug;12(8):602-13

Liver adenoma Liver

1.7

References: Little CC, Am J Cancer 1939;36(3):431-450

Liver carcinoma Liver

0.4

References: Little CC, Am J Cancer 1939;36(3):431-450

Liver hepatoma Liver

0

0

References: Flaks A, Eur J Cancer 1968 Dec;4(6):579-85

Liver hepatoma Liver 9,10-dimethyl-1,2-benzanthracene (DMBA)

3.8

18

References: Flaks A, Eur J Cancer 1968 Dec;4(6):579-85

Liver hepatoma - malignant Liver 9,10-dimethyl-1,2-benzanthracene (DMBA)

0

0

References: Flaks A, Eur J Cancer 1968 Dec;4(6):579-85

Liver tumor Liver

5

References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6

Liver tumor - benign Liver toothpaste (control)

3.85

References: Roe FJ, J Environ Pathol Toxicol 1979 Jan-Feb;2(3):799-819

Liver tumor - benign Liver chloroform   ⋅   toothpaste (control)

0

References: Roe FJ, J Environ Pathol Toxicol 1979 Jan-Feb;2(3):799-819

Liver tumor - malignant Liver toothpaste (control)

0

References: Roe FJ, J Environ Pathol Toxicol 1979 Jan-Feb;2(3):799-819

Liver tumor - malignant Liver chloroform   ⋅   toothpaste (control)

0

References: Roe FJ, J Environ Pathol Toxicol 1979 Jan-Feb;2(3):799-819

Lung adenocarcinoma Lung

0.2

References: Little CC, Am J Cancer 1939;36(3):431-450

Lung adenoma Lung

0

0

References: Flaks A, Eur J Cancer 1968 Dec;4(6):579-85

Lung adenoma Lung 9,10-dimethyl-1,2-benzanthracene (DMBA)

3.8

0

References: Flaks A, Eur J Cancer 1968 Dec;4(6):579-85

Lung carcinoma Lung 9,10-dimethyl-1,2-benzanthracene (DMBA)

0

0

References: Flaks A, Eur J Cancer 1968 Dec;4(6):579-85

Lung tumor Lung

0 - 7.0

References: Heston WE, J Natl Cancer Inst 1942;3():79-82   ⋅   Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6   ⋅   Shimkin MB, Adv Cancer Res 1975;21():1-58   ⋅   Staats J, Companion to Mouse News Lett No. 33 1965;():

Lung tumor Lung urethane (ethyl carbamate)

7.0

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung 4-nitroquinoline-N-oxide (4-NQO)

observed

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung X-radiation

observed

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung cigarette smoke

4.0

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor - benign Lung toothpaste (control)

1.92

References: Roe FJ, J Environ Pathol Toxicol 1979 Jan-Feb;2(3):799-819

Lung tumor - benign Lung chloroform   ⋅   toothpaste (control)

5.77

References: Roe FJ, J Environ Pathol Toxicol 1979 Jan-Feb;2(3):799-819

Lung tumor - locally invasive Lung toothpaste (control)

1.92

References: Roe FJ, J Environ Pathol Toxicol 1979 Jan-Feb;2(3):799-819

Lung tumor - locally invasive Lung chloroform   ⋅   toothpaste (control)

1.92

References: Roe FJ, J Environ Pathol Toxicol 1979 Jan-Feb;2(3):799-819

Lung tumor - malignant Lung toothpaste (control)

0

References: Roe FJ, J Environ Pathol Toxicol 1979 Jan-Feb;2(3):799-819

Lung tumor - malignant Lung chloroform   ⋅   toothpaste (control)

0

References: Roe FJ, J Environ Pathol Toxicol 1979 Jan-Feb;2(3):799-819

Lymphatic vessel lymphangioma Lymphatic vessel

0.5

References: Little CC, Am J Cancer 1939;36(3):431-450

Mammary gland carcinoma Mammary gland

0.5 - 1

References: Little CC, Am J Cancer 1939;36(3):431-450   ⋅   Schlom J, J Natl Cancer Inst 1973;51():541-51

Mammary gland carcinoma Mammary gland 9,10-dimethyl-1,2-benzanthracene (DMBA)

0

References: Flaks A, Eur J Cancer 1968 Dec;4(6):579-85

Mammary gland tumor Mammary gland

0 - 1

0 - low

References: Festing MFW, Mouse Genome 1996;94(3):523-677   ⋅   International Nomenclature Committee, Cancer Res 1952 Aug;12(8):602-13   ⋅   Staats J, Cancer Res 1985 Mar;45(3):945-77   ⋅   Staats J, Companion to Mouse News Lett No. 21 1959;():   ⋅   Staats J, Companion to Mouse News Lett No. 25 1961;():   ⋅   Staats J, Companion to Mouse News Lett No. 33 1965;():   ⋅   Vaidya AB, J Virol 1983 Jun;46(3):818-28

Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast

0

References: Murphy ED, 1966;():521-62

Muscle - Striated - Skeletal rhabdomyosarcoma Muscle - Striated - Skeletal estradiol 17-n-valerate

1.6

References: Szepsenwol J, Oncology 1975;32(2):58-72

Sites of Metastasis: Muscle - Striated - Cardiac , Muscle - Striated - Skeletal - Intercostal
Ovary adenocarcinoma - papillary/cystic Ovary

0.2

References: Little CC, Am J Cancer 1939;36(3):431-450

Ovary carcinoma Ovary 9,10-dimethyl-1,2-benzanthracene (DMBA)

0

References: Flaks A, Eur J Cancer 1968 Dec;4(6):579-85

Pituitary gland adenoma Pituitary gland estrogen

high - very high

References: Festing MFW, Mouse Genome 1996;94(3):523-677   ⋅   Heston WE, 1963;():247-68

Pituitary gland adenoma Pituitary gland

observed

References: Staats J, Cancer Res 1985 Mar;45(3):945-77

Reticular cell reticulum cell neoplasm Reticular cell

10

4

References: Staats J, Companion to Mouse News Lett No. 33 1965;():

Skin - Melanocyte melanoma Skin - Melanocyte

0.2

References: Little CC, Am J Cancer 1939;36(3):431-450

Skin squamous cell carcinoma Skin

7.4

References: Staats J, Companion to Mouse News Lett No. 21 1959;():

Stomach carcinoma - epidermoid Stomach

0.2

References: Little CC, Am J Cancer 1939;36(3):431-450

Uterus tumor Uterus dimethylbenzanthracene (DMBA)

observed

References: Festing MFW, Mouse Genome 1996;94(3):523-677

Vulva tumor Vulva

0.2

References: Little CC, Am J Cancer 1939;36(3):431-450

(Unspecified organ) angioma (Unspecified organ)

1.5

References: Little CC, Am J Cancer 1939;36(3):431-450

(Unspecified organ) endothelioma (Unspecified organ)

2.3 - 4.5

4.0

References: Little CC, Am J Cancer 1939;36(3):431-450

(Unspecified organ) neoplasm (Unspecified organ) toothpaste (control)

3.85

References: Roe FJ, J Environ Pathol Toxicol 1979 Jan-Feb;2(3):799-819

(Unspecified organ) neoplasm (Unspecified organ) chloroform   ⋅   toothpaste (control)

1.92

References: Roe FJ, J Environ Pathol Toxicol 1979 Jan-Feb;2(3):799-819

(Unspecified organ) reticulum cell sarcoma (Unspecified organ)

0.2

2.7

References: Little CC, Am J Cancer 1939;36(3):431-450   ⋅   Staats J, Companion to Mouse News Lett No. 33 1965;():

(Unspecified organ) tumor (Unspecified organ)

sporadic - 20.0

References: International Nomenclature Committee, Cancer Res 1952 Aug;12(8):602-13   ⋅   Staats J, Companion to Mouse News Lett No. 25 1961;():

(Unspecified organ) tumor (Unspecified organ) N-ethyl-N-nitrosourea (N-nitrosoethylurea) (ENU)

0

References: Searle CE, Nature 1972 Dec 29;240(5383):559-60

(Unspecified organ) tumor (Unspecified organ) toothpaste (control)

30.77

References: Roe FJ, J Environ Pathol Toxicol 1979 Jan-Feb;2(3):799-819

(Unspecified organ) tumor (Unspecified organ) chloroform   ⋅   toothpaste (control)

23.08

References: Roe FJ, J Environ Pathol Toxicol 1979 Jan-Feb;2(3):799-819

(Unspecified organ) tumor - malignant (Unspecified organ) toothpaste (control)

23.08

References: Roe FJ, J Environ Pathol Toxicol 1979 Jan-Feb;2(3):799-819

(Unspecified organ) tumor - malignant (Unspecified organ) chloroform   ⋅   toothpaste (control)

15.38

References: Roe FJ, J Environ Pathol Toxicol 1979 Jan-Feb;2(3):799-819

(Unspecified organ) tumor - undifferentiated (Unspecified organ)

0.2

References: Little CC, Am J Cancer 1939;36(3):431-450