Strain SummaryFVB/NTac
Strain Name |
FVB/NTac |
Strain Type(s) |
inbred |
Strain Synonym(s) |
FBV/N • FVB • FVB/N • FVB/N from Taconic Farms • FVB/N Taconic Farms • wild-type FVB/N • wt |
Strain Links |
• Festing's List of Inbred Strains |
| Frequency | ||||||||
|---|---|---|---|---|---|---|---|---|
| Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
| Adipose tissue liposarcoma | Subcutis |
1.4 |
0 |
References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6 |
||||
| Adrenal gland - Cortex tumor | Adrenal gland - Cortex |
0 |
References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6 |
|||||
| Adrenal gland - Medulla pheochromocytoma | Adrenal gland - Medulla |
5.6 - 6 |
3.6 - 4 |
observed |
References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105 ⋅ Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6 |
|||
| Adrenal gland - Subcapsular cell hyperplasia | Adrenal gland - Subcapsular cell |
83 |
14 |
References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6 |
||||
| Blood vessel hemangioma | Blood vessel |
0 |
References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6 |
|||||
| Blood vessel hemangioma | Ovary |
1.4 |
References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6 |
|||||
| Blood vessel hemangioma | Spleen |
1.4 |
References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6 |
|||||
| CNS - Brain - Undifferentiated cell tumor | Skin |
2.8 |
6.9 |
References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6 |
||||
| CNS - Brain - Undifferentiated cell tumor | Preputial gland (male) |
3.4 |
References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6 |
|||||
| Connective tissue - Fibroblast fibroma | Uterus |
0 |
References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6 |
|||||
| Eye - Harderian gland adenoma | Eye - Harderian gland |
5.6 |
6.9 |
References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6 |
||||
| Eye - Harderian gland adenoma - acidophilic | Eye - Harderian gland |
observed |
References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105 |
|||||
| Eye - Harderian gland tumor | Eye - Harderian gland |
6 |
7 |
References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6 |
||||
| Gallbladder papilloma | Gallbladder |
1.4 |
0 |
References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6 |
||||
| Leukocyte - Lymphocyte - B-lymphocyte - Follicular center cell lymphoma | Leukocyte - Lymphocyte - B-lymphocyte - Follicular center cell |
5.6 - 6 |
References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6 |
|||||
| Leukocyte - Lymphocyte hyperplasia | Spleen - White pulp |
11 |
0 |
References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6 |
||||
| Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma | Leukocyte - Monocyte - Macrophage - Histiocyte |
observed - 6 |
0 |
References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105 ⋅ Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6 |
||||
| Leukocyte lymphoma | Leukocyte |
observed |
0 |
References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105 ⋅ Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6 |
||||
| Liver - Hepatocyte tumor | Liver - Hepatocyte |
observed |
References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105 |
|||||
| Liver hepatocellular adenoma | Liver |
0 |
17 |
References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6 |
||||
| Liver hepatocellular carcinoma | Liver |
0 |
14 |
References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6 Sites of Metastasis: Lung |
||||
| Liver tumor | Liver |
0 |
20.0 - 21.0 |
References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6 |
||||
| Lung - Alveolus hyperplasia | Lung - Alveolus |
11 |
6.9 |
References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6 |
||||
| Lung adenoma | Lung |
18 |
28 |
References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6 |
||||
| Lung carcinoma | Lung |
21 |
28 |
References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6 |
||||
| Lung neoplasm | Lung |
observed |
References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105 |
|||||
| Lung tumor | Lung |
2.9 - 37 |
41 |
observed |
References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105 ⋅ Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6 ⋅ Torres-Arzayus MI, Cancer Cell 2004 Sep;6(3):263-74 |
|||
| Mammary gland tumor | Mammary gland |
0 - observed |
References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105 ⋅ Torres-Arzayus MI, Cancer Cell 2004 Sep;6(3):263-74 |
|||||
| Muscle - Smooth leiomyoma | Uterus |
0 |
References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6 |
|||||
| Muscle - Smooth leiomyosarcoma | Uterus |
1.4 |
References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6 |
|||||
| Neuroectoderm - Neural crest cell tumor | Subcutis |
observed |
References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105 |
|||||
| Ovary - Corpus luteum hyperplasia | Ovary - Corpus luteum | diethylstilbestrol (DES) |
observed |
References: Eastin WC, Toxicol Pathol 2001;29 Suppl():60-80 |
||||
| Ovary - Corpus luteum hyperplasia | Ovary - Corpus luteum | ethinyl estradiol (EE) |
observed |
References: Eastin WC, Toxicol Pathol 2001;29 Suppl():60-80 |
||||
| Ovary - Germ cell teratoma | Ovary - Germ cell |
1.4 |
References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6 |
|||||
| Ovary - Granulosa cell tumor | Ovary - Granulosa cell |
2.8 |
References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6 |
|||||
| Ovary - Sertoli cell tumor | Ovary - Sertoli cell |
1.4 |
References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6 |
|||||
| Ovary cystadenoma | Ovary |
1.4 |
References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6 |
|||||
| Ovary tumor | Ovary |
observed - 7 |
References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105 ⋅ Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6 |
|||||
| Pancreas - Islet of Langerhans adenoma | Pancreas - Islet of Langerhans |
0 |
3.4 |
References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6 |
||||
| Pituitary gland - Pars distalis adenoma | Pituitary gland - Pars distalis |
14 |
0 |
References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6 |
||||
| Pituitary gland - Pars distalis hyperplasia | Pituitary gland - Pars distalis |
7.2 |
0 |
References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6 |
||||
| Pituitary gland - Pars distalis tumor | Pituitary gland - Pars distalis |
15 |
References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6 |
|||||
| Pituitary gland adenoma | Pituitary gland |
observed |
References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105 |
|||||
| Pituitary gland prolactinoma | Pituitary gland |
observed |
References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105 |
|||||
| Pituitary gland tumor | Pituitary gland |
1.9 |
References: Torres-Arzayus MI, Cancer Cell 2004 Sep;6(3):263-74 |
|||||
| Placenta - Trophoblast choriocarcinoma | Uterus |
0 |
References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6 |
|||||
| Skin - Epidermis squamous cell papilloma | Skin - Epidermis |
1.4 |
0 |
References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6 |
||||
| Skin carcinoma | Skin - Dorsal region | 12-O-tetradecanoylphorbol-13-acetate (TPA) |
observed |
References: Tober KL, Biochem Biophys Res Commun 1998 Jun 29;247(3):644-53 |
||||
| Skin papilloma | Skin - Dorsal region | 12-O-tetradecanoylphorbol-13-acetate (TPA) |
observed |
References: Tober KL, Biochem Biophys Res Commun 1998 Jun 29;247(3):644-53 |
||||
| Skin papilloma | Skin - Dorsal region | ultraviolet radiation (UV) |
0 - 10 |
References: Trempus CS, J Invest Dermatol 1998 Sep;111(3):445-51 |
||||
| Skin papilloma | Skin - Dorsal region | 12-O-tetradecanoylphorbol-13-acetate (TPA) ⋅ dimethylbenzanthracene (DMBA) |
observed |
References: Hansen LA, Carcinogenesis 1996 Sep;17(9):1825-33 |
||||
| Skin squamous cell carcinoma | Skin - Dorsal region | 12-O-tetradecanoylphorbol-13-acetate (TPA) ⋅ dimethylbenzanthracene (DMBA) |
observed |
References: Hansen LA, Carcinogenesis 1996 Sep;17(9):1825-33 |
||||
| Skin tumor | Skin | wounding |
0 |
References: Cannon RE, Mol Carcinog 1997 Sep;20(1):108-14 |
||||
| Stomach - Glandular carcinoma | Stomach - Glandular |
0 |
References: Wang TC, Gastroenterology 2000 Jan;118(1):36-47 |
|||||
| Stomach - Glandular carcinoma | Stomach - Glandular | Helicobacter felis |
0 |
References: Wang TC, Gastroenterology 2000 Jan;118(1):36-47 |
||||
| Stomach - Glandular dysplasia | Stomach - Glandular |
0 |
References: Wang TC, Gastroenterology 2000 Jan;118(1):36-47 |
|||||
| Stomach - Glandular hyperplasia - foveolar | Stomach - Glandular | Helicobacter felis |
observed |
References: Wang TC, Gastroenterology 2000 Jan;118(1):36-47 |
||||
| Stomach - Glandular hyperplasia - foveolar | Stomach - Glandular |
0 |
References: Wang TC, Gastroenterology 2000 Jan;118(1):36-47 |
|||||
| Stomach - Glandular metaplasia | Stomach - Glandular |
0 |
References: Wang TC, Gastroenterology 2000 Jan;118(1):36-47 |
|||||
| Testis - Leydig cell (Interstitial cell) adenoma | Testis - Leydig cell (Interstitial cell) |
3.4 |
References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6 |
|||||
| Testis - Leydig cell (Interstitial cell) hyperplasia | Testis - Leydig cell (Interstitial cell) |
3.4 |
References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6 |
|||||
| Thyroid gland tumor | Thyroid gland |
0 |
0 |
References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6 |
||||
| Uterus - Endometrium hyperplasia - cystic | Uterus - Endometrium | diethylstilbestrol (DES) |
observed |
References: Eastin WC, Toxicol Pathol 2001;29 Suppl():60-80 |
||||
| Uterus - Endometrium hyperplasia - cystic | Uterus - Endometrium | ethinyl estradiol (EE) |
observed |
References: Eastin WC, Toxicol Pathol 2001;29 Suppl():60-80 |
||||
| (Unspecified organ) lesion | (Unspecified organ) | cyclophosphamide (Cytoxan) |
0 |
References: Eastin WC, Toxicol Pathol 2001;29 Suppl():60-80 |
||||
| (Unspecified organ) tumor | (Unspecified organ) |
4.8 |
References: Torres-Arzayus MI, Cancer Cell 2004 Sep;6(3):263-74 |
|||||