Strain SummaryA/J

Strain Name	A/J
Strain Type(s)	inbred
Strain Synonym(s)	A • A/Cloudman • AJ • A/Jax • A/J, H-2^a • A/J-Jax • A/Lilly • strain A • Strain A
Strain Links	• Mouse Phenome Database (MPD) • Festing's List of Inbred Strains • JAX Mice
Strain Genetics	List all models in MMHCdb carrying the H2^a allele H2^a / H2^a
	List all models in MMHCdb carrying the Kras^a allele Kras^a / Kras^a

Models
392 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Adipose tissue - White lipoma	Adipose tissue - White		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Adipose tissue lipoma	Peritoneal cavity		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Adipose tissue lipoma - pedunculated	Peritoneum - Mesentery			observed			References: Sundberg J, MGI Direct Data Submission 2007;(): 6 pathology image(s)
Adipose tissue lipoma - pedunculated	Adipose tissue		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Adrenal gland - Cortex adenoma	Adrenal gland - Cortex		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Adrenal gland - Cortex hyperplasia - nodular	Adrenal gland - Cortex			observed			References: Sundberg J, MGI Direct Data Submission 2007;():
Adrenal gland - Medulla pheochromocytoma	Adrenal gland - Medulla		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Adrenal gland - Subcapsular cell hyperplasia	Adrenal gland - Cortex		60	20			References: Kim JS, Exp Anim 1997 Oct;46(4):303-6
Adrenal gland - Subcapsular cell hyperplasia - spindle cell	Adrenal gland - Subcapsular cell		moderate	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Adrenal gland hyperplasia	Adrenal gland		observed				References: Sundberg J, MGI Direct Data Submission 2007;():
Adrenal gland hyperplasia - nodular	Adrenal gland		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Adrenal gland hyperplasia - spindle cell	Adrenal gland		observed				References: Sundberg J, MGI Direct Data Submission 2007;():
Adrenal gland tumor - carcinoid	Adrenal gland		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Blood vessel hemangioma	Blood vessel		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Blood vessel hemangioma	Uterus		0				References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Blood vessel hemangioma - capillary	Muscle - Striated - Skeletal		observed				References: Sundberg J, MGI Direct Data Submission 2007;(): 4 pathology image(s)
Blood vessel hemangioma - cavernous	Blood vessel		observed	observed			References: Booth CJ, Lab Anim Sci 1995 Oct;45(5):497-502
Blood vessel hemangiosarcoma	Blood vessel		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Blood vessel hemangiosarcoma	Liver		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Blood vessel hemangiosarcoma	Muscle - Striated - Skeletal		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Bone hyperplasia	Bone		0 - observed	0			References: Sundberg J, MGI Direct Data Submission 2007;(): ⋅ Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Bone lesion - fibro-osseous	Bone		0	0	0		References: Berndt A, Exp Mol Pathol 2015 Nov 14;(): ⋅ Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Epididymis cyst	Epididymis			0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Erythrocyte leukemia - erythroleukemia	Spleen		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Erythrocyte neoplasm	Erythrocyte		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Esophagus hyperplasia	Esophagus		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Eye - Harderian gland adenoma	Eye - Harderian gland		observed				References: Sundberg J, MGI Direct Data Submission 2007;(): 4 pathology image(s)
Eye - Lacrimal gland hyperplasia	Eye - Lacrimal gland			observed			References: Sundberg J, MGI Direct Data Submission 2007;():
Forestomach carcinoma in situ	Forestomach	N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)	observed				References: Wang ZY, Cancer Res 1992 Apr 1;52(7):1943-7
Forestomach carcinoma in situ	Forestomach	green tea ⋅ N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)	observed				References: Wang ZY, Cancer Res 1992 Apr 1;52(7):1943-7
Forestomach hyperplasia	Forestomach	N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)	observed				References: Wang ZY, Cancer Res 1992 Apr 1;52(7):1943-7
Forestomach hyperplasia	Forestomach	green tea ⋅ N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)	observed				References: Wang ZY, Cancer Res 1992 Apr 1;52(7):1943-7
Forestomach hyperplasia	Forestomach			observed			References: Sundberg J, Personal Communication 1997;():
Forestomach hyperplasia - papillary	Forestomach		0 - observed	0			References: Sundberg J, MGI Direct Data Submission 2007;(): ⋅ Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Forestomach papilloma	Forestomach	benzo[a]pyrene (BP) (BaP) (B[a]P)	observed				References: Estensen RD, Carcinogenesis 1993 Sep;14(9):1975-7
Forestomach papilloma	Forestomach	benzo[a]pyrene (BP) (BaP) (B[a]P) ⋅ myo-inositol	observed				References: Estensen RD, Carcinogenesis 1993 Sep;14(9):1975-7
Forestomach papilloma	Forestomach	benzo[a]pyrene (BP) (BaP) (B[a]P) ⋅ dexamethasone (DEX)	observed				References: Estensen RD, Carcinogenesis 1993 Sep;14(9):1975-7
Forestomach papilloma	Forestomach	benzo[a]pyrene (BP) (BaP) (B[a]P) ⋅ dexamethasone (DEX) ⋅ myo-inositol	observed				References: Estensen RD, Carcinogenesis 1993 Sep;14(9):1975-7
Forestomach papilloma	Forestomach		0				References: Prokopczyk B, Cancer Lett 2000 Dec 8;161(1):35-46 ⋅ Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Forestomach papilloma	Forestomach	benzo[a]pyrene (BP) (BaP) (B[a]P) ⋅ 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)	85 - 100				References: Prokopczyk B, Cancer Lett 2000 Dec 8;161(1):35-46
Forestomach papilloma	Forestomach	benzo[a]pyrene (BP) (BaP) (B[a]P) ⋅ 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) ⋅ 1,4-phenylenebis(methylene)selenocyanate (p-XSC)	50 - 100				References: Prokopczyk B, Cancer Lett 2000 Dec 8;161(1):35-46
Forestomach papilloma	Forestomach	N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)	observed				References: Wang ZY, Cancer Res 1992 Apr 1;52(7):1943-7
Forestomach papilloma	Forestomach	green tea ⋅ N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)	observed				References: Wang ZY, Cancer Res 1992 Apr 1;52(7):1943-7
Forestomach squamous cell carcinoma	Forestomach	N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)	observed				References: Wang ZY, Cancer Res 1992 Apr 1;52(7):1943-7
Forestomach squamous cell carcinoma	Forestomach	green tea ⋅ N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)	observed				References: Wang ZY, Cancer Res 1992 Apr 1;52(7):1943-7
Forestomach tumor	Forestomach		0				References: Wang ZY, Cancer Res 1992 Apr 1;52(7):1943-7
Forestomach tumor	Forestomach	green tea	0				References: Wang ZY, Cancer Res 1992 Apr 1;52(7):1943-7
Forestomach tumor	Forestomach	N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)	98 - 100				References: Wang ZY, Cancer Res 1992 Apr 1;52(7):1943-7
Forestomach tumor	Forestomach	green tea ⋅ N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)	72 - 97				References: Wang ZY, Cancer Res 1992 Apr 1;52(7):1943-7
Gallbladder cyst	Gallbladder		0	observed - moderate			References: Sundberg J, MGI Direct Data Submission 2007;(): ⋅ Sundberg J, Personal Communication 1997;(): ⋅ Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1(): 2 pathology image(s)
Gallbladder hyperplasia	Gallbladder		0	0 - observed			References: Sundberg J, Personal Communication 1997;(): ⋅ Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Gallbladder hyperplasia - papillary	Gallbladder		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Gastrointestinal tract carcinoma	Gastrointestinal tract	N-ethyl-N-nitrosourea (N-nitrosoethylurea) (ENU)			observed		References: Fenske TS, Cancer Res 2006 May 15;66(10):5029-38
Intestine - Large Intestine - Cecum hyperplasia	Intestine - Large Intestine - Cecum		observed - moderate	0			References: Sundberg J, MGI Direct Data Submission 2007;(): ⋅ Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Intestine - Large Intestine - Colon - Distal adenocarcinoma	Intestine - Large Intestine - Colon - Distal	azoxymethane (AOM)		observed			References: Nambiar PR, Int J Oncol 2003 Jan;22(1):145-50
Intestine - Large Intestine - Colon - Distal adenoma - polypoid	Intestine - Large Intestine - Colon - Distal	azoxymethane (AOM)		observed			References: Papanikolaou A, Cancer Lett 1998 Aug 14;130(1-2):29-34
Intestine - Large Intestine - Colon - Distal foci - aberrant crypt (ACF)	Intestine - Large Intestine - Colon - Distal	azoxymethane (AOM)		observed			References: Nambiar PR, Int J Oncol 2003 Jan;22(1):145-50 ⋅ Papanikolaou A, Cancer Lett 1998 Aug 14;130(1-2):29-34
Intestine - Large Intestine - Colon - Distal foci - aberrant crypt (ACF)	Intestine - Large Intestine - Colon - Distal			0			References: Papanikolaou A, Cancer Lett 1998 Aug 14;130(1-2):29-34
Intestine - Large Intestine - Colon - Distal squamous cell carcinoma	Intestine - Large Intestine - Colon - Distal	azoxymethane (AOM)		observed			References: Nambiar PR, Int J Oncol 2003 Jan;22(1):145-50
Intestine - Large Intestine - Colon - Distal tumor	Intestine - Large Intestine - Colon - Distal	azoxymethane (AOM)		observed - 100			References: Nambiar PR, Int J Oncol 2003 Jan;22(1):145-50 ⋅ Papanikolaou A, Cancer Lett 1998 Aug 14;130(1-2):29-34
Intestine - Large Intestine - Colon - Distal tumor	Intestine - Large Intestine - Colon - Distal			0			References: Papanikolaou A, Cancer Lett 1998 Aug 14;130(1-2):29-34
Intestine - Large Intestine - Colon - Proximal tumor	Intestine - Large Intestine - Colon - Proximal	azoxymethane (AOM)		0			References: Nambiar PR, Int J Oncol 2003 Jan;22(1):145-50 ⋅ Papanikolaou A, Cancer Lett 1998 Aug 14;130(1-2):29-34
Intestine - Large Intestine - Colon - Proximal tumor	Intestine - Large Intestine - Colon - Proximal			0			References: Papanikolaou A, Cancer Lett 1998 Aug 14;130(1-2):29-34
Intestine - Large Intestine - Colon adenoma	Intestine - Large Intestine - Colon		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Intestine - Large Intestine - Colon tumor	Intestine - Large Intestine - Colon	azoxymethane (AOM)		observed			References: Guda K, Cancer Lett 2003 Feb 28;191(1):17-25
Intestine - Large Intestine - Colon tumor	Intestine - Large Intestine - Colon	dextran sulfate sodium (DSS) ⋅ azoxymethane (AOM)			100		References: Van Der Kraak L, Mamm Genome 2016 Jun;27(5-6):213-24
Intestine - Large Intestine tumor	Intestine - Large Intestine	dextran sulfate sodium (DSS) ⋅ azoxymethane (AOM)			100		References: Van Der Kraak L, Mamm Genome 2016 Jun;27(5-6):213-24
Intestine - Small Intestine - Brunner's gland adenoma	Intestine - Small Intestine - Brunner's gland		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Intestine - Small Intestine - Brunner's gland hyperplasia	Intestine - Small Intestine - Brunner's gland		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Intestine - Small Intestine - Duodenum adenocarcinoma in situ	Intestine - Small Intestine - Duodenum			observed			References: Sundberg J, MGI Direct Data Submission 2007;(): 5 pathology image(s)
Intestine - Small Intestine - Duodenum adenoma	Intestine - Small Intestine - Duodenum		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Intestine - Small Intestine - Duodenum cyst	Intestine - Small Intestine - Duodenum		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Intestine - Small Intestine - Duodenum hyperplasia	Intestine - Small Intestine - Duodenum		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Intestine - Small Intestine - Duodenum polyp	Intestine - Small Intestine - Duodenum		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Intestine - Small Intestine - Ileum polyp	Intestine - Small Intestine - Ileum		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Intestine - Small Intestine - Jejunum hyperplasia	Intestine - Small Intestine - Jejunum		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Intestine - Small Intestine - Jejunum polyp	Intestine - Small Intestine - Jejunum		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Intestine - Small Intestine normal tissue (control)	Intestine - Small Intestine			not applicable			References: Lyons BL, Personal Communication 2004;(): 6 pathology image(s)
Intestine - Small Intestine tumor	Intestine - Small Intestine			0			References: Papanikolaou A, Cancer Lett 1998 Aug 14;130(1-2):29-34
Intestine - Small Intestine tumor	Intestine - Small Intestine	azoxymethane (AOM)		0			References: Papanikolaou A, Cancer Lett 1998 Aug 14;130(1-2):29-34
Kidney - Renal tubule adenoma	Kidney - Renal tubule			observed			References: Sundberg J, MGI Direct Data Submission 2007;(): 4 pathology image(s)
Kidney adenoma	Kidney		0	observed - low	1		References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35 ⋅ Sundberg J, MGI Direct Data Submission 2007;(): ⋅ Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Kidney tumor	Kidney			0			References: Papanikolaou A, Cancer Lett 1998 Aug 14;130(1-2):29-34
Kidney tumor	Kidney	azoxymethane (AOM)		0			References: Papanikolaou A, Cancer Lett 1998 Aug 14;130(1-2):29-34
Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell tumor	Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Leukocyte - Lymphocyte leukemia - lymphocytic	Leukocyte - Lymphocyte		1	1		1	References: Festing MFW, Mouse Genome 1996;94(3):523-677 ⋅ Hoag WG, Ann N Y Acad Sci 1963 Nov 4;108():805-831
Leukocyte - Lymphocyte lymphoma	Leukocyte - Lymphocyte	N-ethyl-N-nitrosourea (N-nitrosoethylurea) (ENU)			0		References: Fenske TS, Cancer Res 2006 May 15;66(10):5029-38
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma	Leukocyte - Monocyte - Macrophage - Histiocyte		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma	Spleen		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor	Lung				1		References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35
Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor	Eye - Eyelid		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor	Lymph node		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor	Skin		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Leukocyte - Myelocyte (Granulocyte) hyperplasia	Bone marrow		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Leukocyte - Myelocyte (Granulocyte) tumor - malignant	Leukocyte - Myelocyte (Granulocyte)	N-ethyl-N-nitrosourea (N-nitrosoethylurea) (ENU)			0		References: Fenske TS, Cancer Res 2006 May 15;66(10):5029-38
Leukocyte leukemia	Leukocyte		1.6 - 3.1				References: Myers DD, Life Sci 1970;9(Pt II):1071-80
Leukocyte leukemia	Leukocyte	Friend leukemia virus - "regressing" (RFV)		70			References: Dietz M, Int J Cancer 1972 Jul 15;10(1):99-104
Leukocyte leukemia	Leukocyte	Friend leukemia virus - "conventional" (CFV)		82			References: Dietz M, Int J Cancer 1972 Jul 15;10(1):99-104
Leukocyte lymphoma	Leukocyte		0	0 - observed	1		References: Coleman D, Personal Communication 2024;(): ⋅ Shimkin MB, J Natl Cancer Inst 1966;36():915-35 ⋅ Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1(): 3 pathology image(s)
Liver - Bile duct adenoma	Liver - Bile duct		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Liver - Bile duct hyperplasia	Liver - Bile duct		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Liver hepatoma	Liver		0	0	1		References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35 ⋅ Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Liver tumor	Liver			0			References: Papanikolaou A, Cancer Lett 1998 Aug 14;130(1-2):29-34
Liver tumor	Liver	azoxymethane (AOM)		0			References: Papanikolaou A, Cancer Lett 1998 Aug 14;130(1-2):29-34
Lung - Alveolus adenoma	Lung - Alveolus		0 - 51	34			References: Adkins B Jr, J Toxicol Environ Health 1986;17(2-3):311-22 ⋅ Yang GY, Carcinogenesis 1997 Dec;18(12):2361-5
Lung - Alveolus adenoma	Lung - Alveolus	theaflavins	0				References: Yang GY, Carcinogenesis 1997 Dec;18(12):2361-5
Lung - Alveolus adenoma	Lung - Alveolus	4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)	observed - 100				References: Belinsky SA, Cancer Res 1992 Jun 1;52(11):3164-73 ⋅ Rioux N, Cancer Res 1998 Dec 1;58(23):5354-60 ⋅ Yang GY, Carcinogenesis 1997 Dec;18(12):2361-5 ⋅ Yao R, Exp Lung Res 2000 Dec;26(8):731-42
Lung - Alveolus adenoma	Lung - Alveolus	4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) ⋅ theaflavins	100				References: Yang GY, Carcinogenesis 1997 Dec;18(12):2361-5
Lung - Alveolus adenoma	Lung - Alveolus	vinyl chloride (chloroethylene)	74 - 100	88 - 100			References: Adkins B Jr, J Toxicol Environ Health 1986;17(2-3):311-22
Lung - Alveolus adenoma	Lung - Alveolus	carbon disulfide	39				References: Adkins B Jr, J Toxicol Environ Health 1986;17(2-3):311-22
Lung - Alveolus adenoma	Lung - Alveolus	1,2-dibromoethane	68 - 100				References: Adkins B Jr, J Toxicol Environ Health 1986;17(2-3):311-22
Lung - Alveolus adenoma	Lung - Alveolus	ethylene oxide	42 - 87				References: Adkins B Jr, J Toxicol Environ Health 1986;17(2-3):311-22
Lung - Alveolus adenoma	Lung - Alveolus	naphthalene	29 - 30				References: Adkins B Jr, J Toxicol Environ Health 1986;17(2-3):311-22
Lung - Alveolus adenoma	Lung - Alveolus	nitrogen dioxide	observed - 12				References: Adkins B Jr, J Toxicol Environ Health 1986;17(2-3):311-22
Lung - Alveolus adenoma	Lung - Alveolus	urethane (ethyl carbamate)	100	100			References: Adkins B Jr, J Toxicol Environ Health 1986;17(2-3):311-22
Lung - Alveolus adenoma	Lung - Alveolus	4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) ⋅ aspirin (acetylsalicylic acid) (ASA)	observed - 100				References: Rioux N, Cancer Res 1998 Dec 1;58(23):5354-60 ⋅ Yao R, Exp Lung Res 2000 Dec;26(8):731-42
Lung - Alveolus adenoma	Lung - Alveolus	4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) ⋅ acetaminophen	100				References: Rioux N, Cancer Res 1998 Dec 1;58(23):5354-60
Lung - Alveolus adenoma	Lung - Alveolus	4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) ⋅ NS-398	observed - 100				References: Rioux N, Cancer Res 1998 Dec 1;58(23):5354-60 ⋅ Yao R, Exp Lung Res 2000 Dec;26(8):731-42
Lung - Alveolus adenoma	Lung - Alveolus	vinyl carbamate (VC)		observed			References: Foley JF, Exp Lung Res 1991 Mar-Apr;17(2):157-68
Lung - Alveolus carcinoma	Lung - Alveolus	4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)	observed				References: Belinsky SA, Cancer Res 1992 Jun 1;52(11):3164-73
Lung - Alveolus carcinoma	Lung - Alveolus	vinyl carbamate (VC)		observed			References: Foley JF, Exp Lung Res 1991 Mar-Apr;17(2):157-68
Lung - Alveolus hyperplasia	Lung - Alveolus	4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)	observed				References: Belinsky SA, Cancer Res 1992 Jun 1;52(11):3164-73 ⋅ Yang G, Cancer Res 1997 May 15;57(10):1889-94 ⋅ Yang GY, Carcinogenesis 1997 Dec;18(12):2361-5
Lung - Alveolus hyperplasia	Lung - Alveolus	4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) ⋅ theaflavins	observed				References: Yang GY, Carcinogenesis 1997 Dec;18(12):2361-5
Lung - Alveolus hyperplasia	Lung - Alveolus	1,2-dibromoethane	observed				References: Adkins B Jr, J Toxicol Environ Health 1986;17(2-3):311-22
Lung - Alveolus hyperplasia	Lung - Alveolus	vinyl carbamate (VC)		observed			References: Foley JF, Exp Lung Res 1991 Mar-Apr;17(2):157-68
Lung - Alveolus lesion	Lung - Alveolus			0 - 50			References: Foley JF, Exp Lung Res 1991 Mar-Apr;17(2):157-68
Lung - Alveolus lesion	Lung - Alveolus	vinyl carbamate (VC)		100			References: Foley JF, Exp Lung Res 1991 Mar-Apr;17(2):157-68
Lung - Bronchiole adenoma	Lung - Bronchiole	1,2-dibromoethane	observed				References: Adkins B Jr, J Toxicol Environ Health 1986;17(2-3):311-22
Lung - Bronchiole hyperplasia	Lung - Bronchiole	4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)	observed				References: Yang G, Cancer Res 1997 May 15;57(10):1889-94
Lung - Bronchiole hyperplasia	Lung - Bronchiole	1,2-dibromoethane	observed				References: Adkins B Jr, J Toxicol Environ Health 1986;17(2-3):311-22
Lung - Club cell carcinoma	Lung - Club cell	radon		11			References: Groch KM, Int J Radiat Biol 1997 Mar;71(3):301-8
Lung adenocarcinoma	Lung	4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)	80	observed		observed	References: Belinsky SA, Carcinogenesis 1997 Jan;18(1):115-20 ⋅ Sabourin CL, Exp Lung Res 1998 Jul-Aug;24(4):499-521 ⋅ Yang G, Cancer Res 1997 May 15;57(10):1889-94
Lung adenocarcinoma	Lung	4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) ⋅ black tea	58				References: Yang G, Cancer Res 1997 May 15;57(10):1889-94
Lung adenocarcinoma	Lung	1-nitropyrene (1-NP)		observed			References: Bai F, Mol Carcinog 1998 Aug;22(4):258-64
Lung adenocarcinoma	Lung		0	0			References: Bai F, Mol Carcinog 1998 Aug;22(4):258-64 ⋅ Kim SH, Anticancer Res 1996 Jan-Feb;16(1):465-70
Lung adenocarcinoma	Lung	urethane (ethyl carbamate)		observed - very high		observed	References: Bauer AK, Carcinogenesis 2000 Apr;21(4):543-50 ⋅ Stearman RS, Am J Pathol 2005 Dec;167(6):1763-75 ⋅ You M, Proc Natl Acad Sci U S A 1989 May;86(9):3070-4
Lung adenocarcinoma	Lung	benzo[a]pyrene (BP) (BaP) (B[a]P)	25 - 48				References: Kim SH, Anticancer Res 1996 Jan-Feb;16(1):465-70
Lung adenocarcinoma - mixed	Lung	4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)	observed				References: Yang G, Cancer Res 1997 May 15;57(10):1889-94
Lung adenocarcinoma - papillary	Lung	4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)	observed				References: Yang G, Cancer Res 1997 May 15;57(10):1889-94
Lung adenocarcinoma - solid	Lung	4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)	observed				References: Yang G, Cancer Res 1997 May 15;57(10):1889-94
Lung adenoma	Lung	4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)	96 - 100	observed		60 - 100	References: Carlton PS, Cancer Lett 2000 Oct 31;159(2):113-7 ⋅ Devereux TR, Mol Carcinog 1993;8(3):177-85 ⋅ Duperron C, Carcinogenesis 1997 May;18(5):1001-6 ⋅ Lantry LE, Carcinogenesis 2000 Jan;21(1):113-6 ⋅ Sabourin CL, Exp Lung Res 1998 Jul-Aug;24(4):499-521 ⋅ Wang ZY, Cancer Res 1992 Apr 1;52(7):1943-7 ⋅ Yang G, Cancer Res 1997 May 15;57(10):1889-94
Lung adenoma	Lung	tricaprylin (trioctanoin)		50			References: Prahalad AK, Carcinogenesis 1997 Oct;18(10):1955-63
Lung adenoma	Lung	dibenzo[a,l]pyrene (DB[a,l]P)		43 - 100			References: Prahalad AK, Carcinogenesis 1997 Oct;18(10):1955-63
Lung adenoma	Lung	urethane (ethyl carbamate)		observed - 100	100	observed - 100	References: Bauer AK, Carcinogenesis 2000 Apr;21(4):543-50 ⋅ Horio Y, Mol Carcinog 1996 Dec;17(4):217-23 ⋅ Malkinson AM, J Natl Cancer Inst 1983 May;70(5):931-6 ⋅ Malkinson AM, J Natl Cancer Inst 1985 Nov;75(5):971-4 ⋅ Mason RJ, Am J Pathol 2000 Jan;156(1):175-82 ⋅ McNeill DA, Drug Chem Toxicol 1990;13(1):71-86 ⋅ McNeill DA, Drug Chem Toxicol 1990;13(1):87-92 ⋅ Prahalad AK, Carcinogenesis 1997 Oct;18(10):1955-63 ⋅ Ruch RJ, Exp Lung Res 2001 Apr-May;27(3):231-43 ⋅ Stearman RS, Am J Pathol 2005 Dec;167(6):1763-75 ⋅ Thaete LG, Cancer Lett 1991 Dec 9;61(1):15-20 ⋅ You M, Proc Natl Acad Sci U S A 1989 May;86(9):3070-4
Lung adenoma	Lung	benzo[a]pyrene (BP) (BaP) (B[a]P)	0 - very high	observed	71 - 95	observed - 74	References: Carlton PS, Cancer Lett 2000 Oct 31;159(2):113-7 ⋅ Chen B, Carcinogenesis 1994 Sep;15(9):2031-5 ⋅ Estensen RD, Carcinogenesis 1993 Sep;14(9):1975-7 ⋅ Estensen RD, Carcinogenesis 2004 Feb;25(2):197-201 ⋅ Kim SH, Anticancer Res 1996 Jan-Feb;16(1):465-70 ⋅ Prahalad AK, Carcinogenesis 1997 Oct;18(10):1955-63 ⋅ Wattenberg LW, Carcinogenesis 2000 Feb;21(2):179-82 ⋅ You M, Proc Natl Acad Sci U S A 1989 May;86(9):3070-4
Lung adenoma	Lung	benzo[b]fluoranthene (B[b]F)		observed			References: Prahalad AK, Carcinogenesis 1997 Oct;18(10):1955-63
Lung adenoma	Lung	cyclopental[c,d]pyrene (CPP)		observed			References: Prahalad AK, Carcinogenesis 1997 Oct;18(10):1955-63
Lung adenoma	Lung	5-methylchrysene (5-MeC)		observed			References: Prahalad AK, Carcinogenesis 1997 Oct;18(10):1955-63
Lung adenoma	Lung	4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) ⋅ black tea	100				References: Yang G, Cancer Res 1997 May 15;57(10):1889-94
Lung adenoma	Lung		0 - high	observed - 80	3.2 - 42	11 - 50	References: Bai F, Mol Carcinog 1998 Aug;22(4):258-64 ⋅ Bauer AK, Carcinogenesis 2000 Apr;21(4):543-50 ⋅ Berndt A, Cancer Res 2011 Sep 1;71(17):5779-91 ⋅ Carlton PS, Cancer Lett 2000 Oct 31;159(2):113-7 ⋅ Chen B, Carcinogenesis 1994 Sep;15(9):2031-5 ⋅ D'Agostini F, Int J Oncol 2001 Mar;18(3):607-15 ⋅ Duperron C, Carcinogenesis 1997 May;18(5):1001-6 ⋅ Gordon T, Cancer Lett 2009 Mar 18;275(2):213-20 ⋅ Groch KM, Int J Radiat Biol 1997 Mar;71(3):301-8 ⋅ Kim SH, Anticancer Res 1996 Jan-Feb;16(1):465-70 ⋅ McNeill DA, Drug Chem Toxicol 1990;13(1):71-86 ⋅ McNeill DA, Drug Chem Toxicol 1990;13(1):87-92 ⋅ Prahalad AK, Carcinogenesis 1997 Oct;18(10):1955-63 ⋅ Prokopczyk B, Cancer Lett 2000 Dec 8;161(1):35-46 ⋅ Rioux N, Cancer Res 1998 Dec 1;58(23):5354-60 ⋅ Sundberg J, MGI Direct Data Submission 2007;(): ⋅ Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1(): ⋅ Wang ZY, Cancer Res 1992 Apr 1;52(7):1943-7 17 pathology image(s)
Lung adenoma	Lung	uranium ore dust		observed			References: Groch KM, Int J Radiat Biol 1997 Mar;71(3):301-8
Lung adenoma	Lung	radon		observed			References: Groch KM, Int J Radiat Biol 1997 Mar;71(3):301-8
Lung adenoma	Lung	1-nitropyrene (1-NP)		very high			References: Bai F, Mol Carcinog 1998 Aug;22(4):258-64
Lung adenoma	Lung	benzotrichloride (BTC)			observed		References: You M, Carcinogenesis 1993 Jun;14(6):1247-9
Lung adenoma	Lung	silica		20			References: McNeill DA, Drug Chem Toxicol 1990;13(1):87-92
Lung adenoma	Lung	nickel subsulfide		0 - 63			References: McNeill DA, Drug Chem Toxicol 1990;13(1):71-86
Lung adenoma	Lung	N-methyl-N-nitrosourea (MNU)				observed	References: You M, Proc Natl Acad Sci U S A 1989 May;86(9):3070-4
Lung adenoma	Lung	4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) ⋅ FTI-276 (farnesyltransferase inhibitor 276)				58	References: Lantry LE, Carcinogenesis 2000 Jan;21(1):113-6
Lung adenoma	Lung	budesonide ⋅ benzo[a]pyrene (BP) (BaP) (B[a]P)	0 - very high				References: Estensen RD, Carcinogenesis 2004 Feb;25(2):197-201 ⋅ Wattenberg LW, Carcinogenesis 2000 Feb;21(2):179-82
Lung adenoma	Lung	benzo[a]pyrene (BP) (BaP) (B[a]P) ⋅ budesonide	observed - very high				References: Estensen RD, Carcinogenesis 2004 Feb;25(2):197-201 ⋅ Wattenberg LW, Carcinogenesis 2000 Feb;21(2):179-82
Lung adenoma	Lung	benzo[a]pyrene (BP) (BaP) (B[a]P) ⋅ myo-inositol	observed - very high				References: Estensen RD, Carcinogenesis 1993 Sep;14(9):1975-7 ⋅ Estensen RD, Carcinogenesis 2004 Feb;25(2):197-201 ⋅ Wattenberg LW, Carcinogenesis 2000 Feb;21(2):179-82
Lung adenoma	Lung	benzo[a]pyrene (BP) (BaP) (B[a]P) ⋅ budesonide ⋅ myo-inositol	very high				References: Wattenberg LW, Carcinogenesis 2000 Feb;21(2):179-82
Lung adenoma	Lung	budesonide ⋅ benzo[a]pyrene (BP) (BaP) (B[a]P) ⋅ myo-inositol	observed - very high				References: Estensen RD, Carcinogenesis 2004 Feb;25(2):197-201 ⋅ Wattenberg LW, Carcinogenesis 2000 Feb;21(2):179-82
Lung adenoma	Lung	benzo[a]pyrene (BP) (BaP) (B[a]P) ⋅ beclomethasone dipropionate	very high				References: Wattenberg LW, Carcinogenesis 2000 Feb;21(2):179-82
Lung adenoma	Lung	environmental cigarette smoke (ECS)	30 - 75				References: D'Agostini F, Int J Oncol 2001 Mar;18(3):607-15
Lung adenoma	Lung	environmental cigarette smoke (ECS) ⋅ halogen light	35 - 55				References: D'Agostini F, Int J Oncol 2001 Mar;18(3):607-15
Lung adenoma	Lung	Aroclor 1254	0 - 22				References: D'Agostini F, Int J Oncol 2001 Mar;18(3):607-15
Lung adenoma	Lung	Aroclor 1254 ⋅ environmental cigarette smoke (ECS)	0 - 78				References: D'Agostini F, Int J Oncol 2001 Mar;18(3):607-15
Lung adenoma	Lung	Aroclor 1254 ⋅ butylated hydroxytoluene (BHT)	0 - 56				References: D'Agostini F, Int J Oncol 2001 Mar;18(3):607-15
Lung adenoma	Lung	Aroclor 1254 ⋅ environmental cigarette smoke (ECS) ⋅ butylated hydroxytoluene (BHT)	0 - 56				References: D'Agostini F, Int J Oncol 2001 Mar;18(3):607-15
Lung adenoma	Lung	mainstream cigarette smoke (MCS)	0 - 33				References: D'Agostini F, Int J Oncol 2001 Mar;18(3):607-15 ⋅ Gordon T, Cancer Lett 2009 Mar 18;275(2):213-20
Lung adenoma	Lung	mainstream cigarette smoke condensate (MCSC)	0				References: D'Agostini F, Int J Oncol 2001 Mar;18(3):607-15
Lung adenoma	Lung	urethane (ethyl carbamate) ⋅ butylated hydroxytoluene (BHT)			100		References: Malkinson AM, J Natl Cancer Inst 1983 May;70(5):931-6
Lung adenoma	Lung	benzo[a]pyrene (BP) (BaP) (B[a]P) ⋅ dexamethasone (DEX)	very high				References: Estensen RD, Carcinogenesis 1993 Sep;14(9):1975-7
Lung adenoma	Lung	benzo[a]pyrene (BP) (BaP) (B[a]P) ⋅ dexamethasone (DEX) ⋅ myo-inositol	very high				References: Estensen RD, Carcinogenesis 1993 Sep;14(9):1975-7
Lung adenoma	Lung	4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) ⋅ AIN-76A	13 - 100				References: Hecht SS, Carcinogenesis 1989 Oct;10(10):1901-4
Lung adenoma	Lung	4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) ⋅ NIH-07	4 - 100				References: Hecht SS, Carcinogenesis 1989 Oct;10(10):1901-4
Lung adenoma	Lung	4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) ⋅ NIH-07 ⋅ AIN-76A	100				References: Hecht SS, Carcinogenesis 1989 Oct;10(10):1901-4
Lung adenoma	Lung	AIN-76A	0 - 30				References: Hecht SS, Carcinogenesis 1989 Oct;10(10):1901-4
Lung adenoma	Lung	NIH-07	0 - 12				References: Hecht SS, Carcinogenesis 1989 Oct;10(10):1901-4
Lung adenoma	Lung	dimethylnitrosamine (DMN)			100		References: Chen B, Carcinogenesis 1994 Sep;15(9):2031-5
Lung adenoma	Lung	7,12-dimethylbenz[a]anthracene (DMBA)		observed			References: Pashko LL, Carcinogenesis 1996 Feb;17(2):209-12
Lung adenoma	Lung	calorie restricted ⋅ 7,12-dimethylbenz[a]anthracene (DMBA)		observed			References: Pashko LL, Carcinogenesis 1996 Feb;17(2):209-12
Lung adenoma	Lung	adrenalectomy ⋅ 7,12-dimethylbenz[a]anthracene (DMBA)		observed			References: Pashko LL, Carcinogenesis 1996 Feb;17(2):209-12
Lung adenoma	Lung	adrenalectomy ⋅ calorie restricted ⋅ 7,12-dimethylbenz[a]anthracene (DMBA)		observed			References: Pashko LL, Carcinogenesis 1996 Feb;17(2):209-12
Lung adenoma	Lung	benzo[a]pyrene (BP) (BaP) (B[a]P) ⋅ 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)	100				References: Prokopczyk B, Cancer Lett 2000 Dec 8;161(1):35-46
Lung adenoma	Lung	benzo[a]pyrene (BP) (BaP) (B[a]P) ⋅ 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) ⋅ 1,4-phenylenebis(methylene)selenocyanate (p-XSC)	40 - 100				References: Prokopczyk B, Cancer Lett 2000 Dec 8;161(1):35-46
Lung adenoma	Lung	lyophilized strawberries				20 - 30	References: Carlton PS, Cancer Lett 2000 Oct 31;159(2):113-7
Lung adenoma	Lung	4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) ⋅ lyophilized strawberries				95	References: Carlton PS, Cancer Lett 2000 Oct 31;159(2):113-7
Lung adenoma	Lung	benzo[a]pyrene (BP) (BaP) (B[a]P) ⋅ lyophilized strawberries				79	References: Carlton PS, Cancer Lett 2000 Oct 31;159(2):113-7
Lung adenoma	Lung	green tea	0 - 5.6				References: Wang ZY, Cancer Res 1992 Apr 1;52(7):1943-7
Lung adenoma	Lung	N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)	94 - 100		observed		References: Wang ZY, Cancer Res 1992 Apr 1;52(7):1943-7 ⋅ You M, Carcinogenesis 1992 Sep;13(9):1583-6
Lung adenoma	Lung	green tea ⋅ N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)	46 - 97				References: Wang ZY, Cancer Res 1992 Apr 1;52(7):1943-7
Lung adenoma	Lung	black tea - decaffeinated	4.2				References: Wang ZY, Cancer Res 1992 Apr 1;52(7):1943-7
Lung adenoma	Lung	green tea - decaffeinated	4.0				References: Wang ZY, Cancer Res 1992 Apr 1;52(7):1943-7
Lung adenoma	Lung	4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) ⋅ green tea - decaffeinated	66 - 83				References: Wang ZY, Cancer Res 1992 Apr 1;52(7):1943-7
Lung adenoma	Lung	4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) ⋅ black tea - decaffeinated	83 - 93				References: Wang ZY, Cancer Res 1992 Apr 1;52(7):1943-7
Lung adenoma	Lung	N-ethyl-N-nitrosourea (N-nitrosoethylurea) (ENU)			observed		References: You M, Carcinogenesis 1992 Sep;13(9):1583-6
Lung adenoma	Lung	sulindac ⋅ 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)	100				References: Duperron C, Carcinogenesis 1997 May;18(5):1001-6
Lung adenoma	Lung	4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) ⋅ aspirin (acetylsalicylic acid) (ASA)	93				References: Duperron C, Carcinogenesis 1997 May;18(5):1001-6
Lung adenoma	Lung	4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) ⋅ aspirin - non-buffered	100				References: Duperron C, Carcinogenesis 1997 May;18(5):1001-6
Lung adenoma	Lung	4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) ⋅ aspirin - buffered	100				References: Duperron C, Carcinogenesis 1997 May;18(5):1001-6
Lung carcinoma	Lung		0 - 11.11	0 - observed	0		References: Adkins B Jr, J Toxicol Environ Health 1986;17(2-3):311-22 ⋅ Fenske TS, Cancer Res 2006 May 15;66(10):5029-38 ⋅ Gordon T, Cancer Lett 2009 Mar 18;275(2):213-20 ⋅ Groch KM, Int J Radiat Biol 1997 Mar;71(3):301-8
Lung carcinoma	Lung	uranium ore dust		observed			References: Groch KM, Int J Radiat Biol 1997 Mar;71(3):301-8
Lung carcinoma	Lung	radon		observed			References: Groch KM, Int J Radiat Biol 1997 Mar;71(3):301-8
Lung carcinoma	Lung	1,2-dibromoethane	0				References: Adkins B Jr, J Toxicol Environ Health 1986;17(2-3):311-22
Lung carcinoma	Lung	carbon disulfide	0				References: Adkins B Jr, J Toxicol Environ Health 1986;17(2-3):311-22
Lung carcinoma	Lung	ethylene oxide	0				References: Adkins B Jr, J Toxicol Environ Health 1986;17(2-3):311-22
Lung carcinoma	Lung	naphthalene	0				References: Adkins B Jr, J Toxicol Environ Health 1986;17(2-3):311-22
Lung carcinoma	Lung	nitrogen dioxide	0				References: Adkins B Jr, J Toxicol Environ Health 1986;17(2-3):311-22
Lung carcinoma	Lung	urethane (ethyl carbamate)	0	0 - observed			References: Adkins B Jr, J Toxicol Environ Health 1986;17(2-3):311-22 ⋅ Ruch RJ, Exp Lung Res 2001 Apr-May;27(3):231-43
Lung carcinoma	Lung	vinyl chloride (chloroethylene)	0	0			References: Adkins B Jr, J Toxicol Environ Health 1986;17(2-3):311-22
Lung carcinoma	Lung	benzo[a]pyrene (BP) (BaP) (B[a]P)	0 - observed				References: Estensen RD, Carcinogenesis 2004 Feb;25(2):197-201
Lung carcinoma	Lung	budesonide ⋅ benzo[a]pyrene (BP) (BaP) (B[a]P)	observed				References: Estensen RD, Carcinogenesis 2004 Feb;25(2):197-201
Lung carcinoma	Lung	benzo[a]pyrene (BP) (BaP) (B[a]P) ⋅ budesonide	observed				References: Estensen RD, Carcinogenesis 2004 Feb;25(2):197-201
Lung carcinoma	Lung	budesonide ⋅ benzo[a]pyrene (BP) (BaP) (B[a]P) ⋅ myo-inositol	observed				References: Estensen RD, Carcinogenesis 2004 Feb;25(2):197-201
Lung carcinoma	Lung	benzo[a]pyrene (BP) (BaP) (B[a]P) ⋅ budesonide ⋅ myo-inositol	observed				References: Estensen RD, Carcinogenesis 2004 Feb;25(2):197-201
Lung carcinoma	Lung	benzo[a]pyrene (BP) (BaP) (B[a]P) ⋅ myo-inositol	observed				References: Estensen RD, Carcinogenesis 2004 Feb;25(2):197-201
Lung carcinoma	Lung	mainstream cigarette smoke (MCS)	5				References: Gordon T, Cancer Lett 2009 Mar 18;275(2):213-20
Lung carcinoma	Lung	N-ethyl-N-nitrosourea (N-nitrosoethylurea) (ENU)			75 - 86		References: Fenske TS, Cancer Res 2006 May 15;66(10):5029-38
Lung dysplasia	Lung	4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)	59				References: Yang G, Cancer Res 1997 May 15;57(10):1889-94
Lung dysplasia	Lung	4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) ⋅ black tea	69				References: Yang G, Cancer Res 1997 May 15;57(10):1889-94
Lung hyperplasia	Lung	radon		observed - 10			References: Groch KM, Int J Radiat Biol 1997 Mar;71(3):301-8
Lung hyperplasia	Lung		0 - observed	0 - observed			References: Bai F, Mol Carcinog 1998 Aug;22(4):258-64 ⋅ Bauer AK, Carcinogenesis 2000 Apr;21(4):543-50 ⋅ Gordon T, Cancer Lett 2009 Mar 18;275(2):213-20 ⋅ Groch KM, Int J Radiat Biol 1997 Mar;71(3):301-8 ⋅ Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Lung hyperplasia	Lung	uranium ore dust		observed			References: Groch KM, Int J Radiat Biol 1997 Mar;71(3):301-8
Lung hyperplasia	Lung	urethane (ethyl carbamate)		observed		observed	References: Bauer AK, Carcinogenesis 2000 Apr;21(4):543-50 ⋅ Horio Y, Mol Carcinog 1996 Dec;17(4):217-23
Lung hyperplasia	Lung	1-nitropyrene (1-NP)		very high			References: Bai F, Mol Carcinog 1998 Aug;22(4):258-64
Lung hyperplasia	Lung	benzo[a]pyrene (BP) (BaP) (B[a]P)	0 - very high				References: Estensen RD, Carcinogenesis 2004 Feb;25(2):197-201 ⋅ Kim SH, Anticancer Res 1996 Jan-Feb;16(1):465-70
Lung hyperplasia	Lung	budesonide ⋅ benzo[a]pyrene (BP) (BaP) (B[a]P)	0				References: Estensen RD, Carcinogenesis 2004 Feb;25(2):197-201
Lung hyperplasia	Lung	benzo[a]pyrene (BP) (BaP) (B[a]P) ⋅ budesonide	observed				References: Estensen RD, Carcinogenesis 2004 Feb;25(2):197-201
Lung hyperplasia	Lung	benzo[a]pyrene (BP) (BaP) (B[a]P) ⋅ budesonide ⋅ myo-inositol	observed				References: Estensen RD, Carcinogenesis 2004 Feb;25(2):197-201
Lung hyperplasia	Lung	budesonide ⋅ benzo[a]pyrene (BP) (BaP) (B[a]P) ⋅ myo-inositol	observed				References: Estensen RD, Carcinogenesis 2004 Feb;25(2):197-201
Lung hyperplasia	Lung	benzo[a]pyrene (BP) (BaP) (B[a]P) ⋅ myo-inositol	observed				References: Estensen RD, Carcinogenesis 2004 Feb;25(2):197-201
Lung hyperplasia	Lung	mainstream cigarette smoke (MCS)	observed				References: Gordon T, Cancer Lett 2009 Mar 18;275(2):213-20
Lung metaplasia - squamous	Lung	benzo[a]pyrene (BP) (BaP) (B[a]P)	very high				References: Kim SH, Anticancer Res 1996 Jan-Feb;16(1):465-70
Lung normal tissue (control)	Lung	urethane (ethyl carbamate)		not applicable			References: Stearman RS, Am J Pathol 2005 Dec;167(6):1763-75
Lung papilloma	Lung		0				References: Gordon T, Cancer Lett 2009 Mar 18;275(2):213-20
Lung papilloma	Lung	mainstream cigarette smoke (MCS)	0				References: Gordon T, Cancer Lett 2009 Mar 18;275(2):213-20
Lung squamous cell carcinoma	Lung		0				References: Kim SH, Anticancer Res 1996 Jan-Feb;16(1):465-70
Lung squamous cell carcinoma	Lung	benzo[a]pyrene (BP) (BaP) (B[a]P)	48 - 50				References: Kim SH, Anticancer Res 1996 Jan-Feb;16(1):465-70
Lung tumor	Lung		0 - 100	0 - 81	observed - 59.0	observed - 90	References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105 ⋅ Castonguay A, Exp Lung Res 1998 Jul-Aug;24(4):605-15 ⋅ D'Agostini F, Int J Oncol 2001 Mar;18(3):607-15 ⋅ Devereux TR, Mol Carcinog 1993;8(3):177-85 ⋅ Estensen RD, Carcinogenesis 2004 Feb;25(2):197-201 ⋅ Festing MFW, Mouse Genome 1996;94(3):523-677 ⋅ Gordon T, Cancer Lett 2009 Mar 18;275(2):213-20 ⋅ Gray DL, Exp Lung Res 2001 Apr-May;27(3):245-53 ⋅ Groch KM, Int J Radiat Biol 1997 Mar;71(3):301-8 ⋅ Gunning WT, Exp Lung Res 2000 Dec;26(8):757-72 ⋅ Hoag WG, Ann N Y Acad Sci 1963 Nov 4;108():805-831 ⋅ Russell ES, 1966;():511-519 ⋅ Ryan J, J Natl Cancer Inst 1987 Dec;79(6):1351-7 ⋅ Shimkin MB, J Natl Cancer Inst 1966;36():915-35 ⋅ Smith GS, J Natl Cancer Inst 1973 May;50(5):1195-213 ⋅ Staats J, Companion to Mouse News Lett No. 21 1959;(): ⋅ Staats J, Companion to Mouse News Lett No. 25 1961;(): ⋅ Witschi H, Carcinogenesis 1997 Mar;18(3):575-86 ⋅ You L, Carcinogenesis 1994 Nov;15(11):2613-8 ⋅ You M, Carcinogenesis 1992 Sep;13(9):1583-6 ⋅ You M, Proc Natl Acad Sci U S A 1992 Jul 1;89(13):5804-8
Lung tumor	Lung	4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)	observed - 100			observed - very high	References: Castonguay A, Exp Lung Res 1998 Jul-Aug;24(4):605-15 ⋅ Devereux TR, Carcinogenesis 1991 Feb;12(2):299-303 ⋅ Devereux TR, Mol Carcinog 1993;8(3):177-85 ⋅ Malkinson AM, Carcinogenesis 1998 Aug;19(8):1353-6 ⋅ Yang G, Cancer Res 1997 May 15;57(10):1889-94
Lung tumor	Lung	uranium ore dust		0 - 60			References: Groch KM, Int J Radiat Biol 1997 Mar;71(3):301-8
Lung tumor	Lung	radon		10 - 72			References: Groch KM, Int J Radiat Biol 1997 Mar;71(3):301-8
Lung tumor	Lung	urethane (ethyl carbamate)		100	observed - 100	observed - 100	References: Chen B, Proc Natl Acad Sci U S A 1994 Feb 15;91(4):1589-93 ⋅ Devereux TR, Mol Carcinog 1993;8(3):177-85 ⋅ Dwyer-Nield LD, Int J Cancer 2010 Jan 1;126(1):125-32 ⋅ Groch KM, Int J Radiat Biol 1997 Mar;71(3):301-8 ⋅ Witschi H, Carcinogenesis 1997 Mar;18(3):575-86
Lung tumor	Lung	environmental tobacco smoke (ETS)		25 - 83			References: Witschi H, Carcinogenesis 1997 Mar;18(3):575-86
Lung tumor	Lung	urethane (ethyl carbamate) ⋅ environmental tobacco smoke (ETS)		100			References: Witschi H, Carcinogenesis 1997 Mar;18(3):575-86
Lung tumor	Lung	3-methylcholanthrene (MCA) (3-MC)		100	observed		References: Dwyer-Nield LD, Int J Cancer 2010 Jan 1;126(1):125-32 ⋅ Witschi H, Carcinogenesis 1997 Mar;18(3):575-86
Lung tumor	Lung	3-methylcholanthrene (MCA) (3-MC) ⋅ environmental tobacco smoke (ETS)		100			References: Witschi H, Carcinogenesis 1997 Mar;18(3):575-86
Lung tumor	Lung	butylated hydroxytoluene (BHT) ⋅ environmental tobacco smoke (ETS)		76			References: Witschi H, Carcinogenesis 1997 Mar;18(3):575-86
Lung tumor	Lung	butylated hydroxytoluene (BHT)		56			References: Witschi H, Carcinogenesis 1997 Mar;18(3):575-86
Lung tumor	Lung	vinyl carbamate (VC)	observed - 100			very high	References: Gunning WT, Exp Lung Res 2000 Dec;26(8):757-72 ⋅ You M, Proc Natl Acad Sci U S A 1992 Jul 1;89(13):5804-8
Lung tumor	Lung	nitrogen mustard (HN2)			29 - 95		References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35
Lung tumor	Lung	mannitol mustard			41 - 91		References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35
Lung tumor	Lung	cyclophosphamide (Cytoxan)			40 - 74		References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35
Lung tumor	Lung	melphalan (L-phenylalanine mustard) (L-sarcolysin)			40 - 98		References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35
Lung tumor	Lung	chlorambucil mustard			47 - 100		References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35
Lung tumor	Lung	uracil mustard			56 - 100		References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35
Lung tumor	Lung	benzalpurine mustard (Elderfield purine mustard)			19 - 45		References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35
Lung tumor	Lung	naphthylamine mustard			40 - 100		References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35
Lung tumor	Lung	aniline mustard			67 - 100		References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35
Lung tumor	Lung	hydroquinone mustard (Weatherbee mustard)			44 - 64		References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35
Lung tumor	Lung	benzimidazole mustard			26 - 100		References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35
Lung tumor	Lung	chloroquine mustard			20 - 80		References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35
Lung tumor	Lung	chloroquine mustard pamoate			27 - 48		References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35
Lung tumor	Lung	5-chloroquine mustard			17 - 45		References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35
Lung tumor	Lung	5-chloroquine mustard pamoate			24 - 58		References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35
Lung tumor	Lung	quinacrine ethyl mustard/2			20 - 67		References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35
Lung tumor	Lung	quinacrine ethyl mustard			24 - 67		References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35
Lung tumor	Lung	quinacrine propyl mustard/2			23 - 37		References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35
Lung tumor	Lung	quinacrine propyl mustard			15 - 30		References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35
Lung tumor	Lung	quinacrine mustard			23 - 46		References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35
Lung tumor	Lung	OPSPA			39 - 83		References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35
Lung tumor	Lung	thioTEPA (thio-TEPA) (TESPA)			29 - 83		References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35
Lung tumor	Lung	aziridyl benzoquinone			36 - 86		References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35
Lung tumor	Lung	mannitol myleran			27 - 100		References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35
Lung tumor	Lung	chloroethylmesulfan			24 - 59		References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35
Lung tumor	Lung	diepoxybutane (L-butadiene epoxide)			21 - 78		References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35
Lung tumor	Lung	diepoxypiperazine			27 - 62		References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35
Lung tumor	Lung	epoxypropidine			14 - 48		References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35
Lung tumor	Lung	epodyl (diglycidyltriethylene glycol)			14 - 71		References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35
Lung tumor	Lung	7H-dibenzo[c,g]carbazole (3,4,5,6-dibenzocarbazole) (DBC)		89 - 100			References: Gray DL, Exp Lung Res 2001 Apr-May;27(3):245-53
Lung tumor	Lung	benzo[a]pyrene (BP) (BaP) (B[a]P)	observed	29 - 100			References: Castonguay A, Exp Lung Res 1998 Jul-Aug;24(4):605-15 ⋅ Estensen RD, Carcinogenesis 2004 Feb;25(2):197-201 ⋅ Gray DL, Exp Lung Res 2001 Apr-May;27(3):245-53
Lung tumor	Lung	benzo[a]pyrene (BP) (BaP) (B[a]P) ⋅ 7H-dibenzo[c,g]carbazole (3,4,5,6-dibenzocarbazole) (DBC)		33 - 100			References: Gray DL, Exp Lung Res 2001 Apr-May;27(3):245-53
Lung tumor	Lung	vinyl carbamate (VC) ⋅ myo-inositol	observed - 100				References: Gunning WT, Exp Lung Res 2000 Dec;26(8):757-72
Lung tumor	Lung	vinyl carbamate (VC) ⋅ dexamethasone (DEX)	observed - 100				References: Gunning WT, Exp Lung Res 2000 Dec;26(8):757-72
Lung tumor	Lung	dexamethasone (DEX) ⋅ vinyl carbamate (VC)	75 - 100				References: Gunning WT, Exp Lung Res 2000 Dec;26(8):757-72
Lung tumor	Lung	piroxicam ⋅ vinyl carbamate (VC)	observed - 100				References: Gunning WT, Exp Lung Res 2000 Dec;26(8):757-72
Lung tumor	Lung	alpha-difluoromethylornithine (DFMO) ⋅ vinyl carbamate (VC)	100				References: Gunning WT, Exp Lung Res 2000 Dec;26(8):757-72
Lung tumor	Lung	green tea extract ⋅ vinyl carbamate (VC)	100				References: Gunning WT, Exp Lung Res 2000 Dec;26(8):757-72
Lung tumor	Lung	alpha-difluoromethylornithine (DFMO) ⋅ dexamethasone (DEX) ⋅ vinyl carbamate (VC)	86				References: Gunning WT, Exp Lung Res 2000 Dec;26(8):757-72
Lung tumor	Lung	green tea extract ⋅ dexamethasone (DEX) ⋅ vinyl carbamate (VC)	79				References: Gunning WT, Exp Lung Res 2000 Dec;26(8):757-72
Lung tumor	Lung	piroxicam ⋅ vinyl carbamate (VC) ⋅ dexamethasone (DEX)	86				References: Gunning WT, Exp Lung Res 2000 Dec;26(8):757-72
Lung tumor	Lung	alpha-difluoromethylornithine (DFMO) ⋅ green tea extract ⋅ vinyl carbamate (VC)	100				References: Gunning WT, Exp Lung Res 2000 Dec;26(8):757-72
Lung tumor	Lung	piroxicam ⋅ alpha-difluoromethylornithine (DFMO) ⋅ vinyl carbamate (VC)	93				References: Gunning WT, Exp Lung Res 2000 Dec;26(8):757-72
Lung tumor	Lung	5-methylchrysene (5-MeC)		65 - 100			References: You L, Carcinogenesis 1994 Nov;15(11):2613-8
Lung tumor	Lung	4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) ⋅ sulindac sulfone	61 - 93				References: Malkinson AM, Carcinogenesis 1998 Aug;19(8):1353-6
Lung tumor	Lung	budesonide	observed				References: Estensen RD, Carcinogenesis 2004 Feb;25(2):197-201
Lung tumor	Lung	benzo[a]pyrene (BP) (BaP) (B[a]P) ⋅ budesonide	observed				References: Estensen RD, Carcinogenesis 2004 Feb;25(2):197-201
Lung tumor	Lung	4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) ⋅ aspirin (acetylsalicylic acid) (ASA)	observed - 100				References: Castonguay A, Exp Lung Res 1998 Jul-Aug;24(4):605-15
Lung tumor	Lung	sulindac ⋅ 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)	observed				References: Castonguay A, Exp Lung Res 1998 Jul-Aug;24(4):605-15
Lung tumor	Lung	A-79175 ⋅ 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)	80				References: Castonguay A, Exp Lung Res 1998 Jul-Aug;24(4):605-15
Lung tumor	Lung	A-79175 ⋅ 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) ⋅ aspirin (acetylsalicylic acid) (ASA)	76				References: Castonguay A, Exp Lung Res 1998 Jul-Aug;24(4):605-15
Lung tumor	Lung	naproxen ⋅ 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)	observed				References: Castonguay A, Exp Lung Res 1998 Jul-Aug;24(4):605-15
Lung tumor	Lung	benzo[a]pyrene (BP) (BaP) (B[a]P) ⋅ sulindac	observed				References: Castonguay A, Exp Lung Res 1998 Jul-Aug;24(4):605-15
Lung tumor	Lung	mainstream cigarette smoke (MCS)	observed - 60				References: Gordon T, Cancer Lett 2009 Mar 18;275(2):213-20
Lung tumor	Lung	3-methylcholanthrene (MCA) (3-MC) ⋅ butylated hydroxytoluene (BHT)			observed		References: Dwyer-Nield LD, Int J Cancer 2010 Jan 1;126(1):125-32
Lymph node cyst	Lymph node		observed - moderate	0			References: Sundberg J, MGI Direct Data Submission 2007;(): ⋅ Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Lymph node hyperplasia	Reticulocyte		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Mammary gland adenocarcinoma	Mammary gland		1 - 28	0	1		References: Festing MFW, Mouse Genome 1996;94(3):523-677 ⋅ Hoag WG, Ann N Y Acad Sci 1963 Nov 4;108():805-831 ⋅ Shimkin MB, J Natl Cancer Inst 1966;36():915-35
Mammary gland tumor	Mammary gland		1 - moderate			20 - moderate	References: International Nomenclature Committee, Cancer Res 1952 Aug;12(8):602-13 ⋅ Russell ES, 1966;():511-519 ⋅ Smith GS, J Natl Cancer Inst 1973 May;50(5):1195-213 ⋅ Staats J, Cancer Res 1985 Mar;45(3):945-77 ⋅ Staats J, Companion to Mouse News Lett No. 21 1959;(): ⋅ Staats J, Companion to Mouse News Lett No. 25 1961;():
Mesodermal cell/mesoblast myxosarcoma	Muscle - Striated - Skeletal		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Mesodermal cell/mesoblast sarcoma	Peritoneal cavity		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Mesodermal cell/mesoblast sarcoma	Seminal vesicle			0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Mesodermal cell/mesoblast sarcoma	Stomach - Glandular		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Mesodermal cell/mesoblast sarcoma	Urinary bladder		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Mesodermal cell/mesoblast sarcoma - stromal	Uterus - Endometrium - Stroma		0				References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Mesothelium mesothelioma	Peritoneal cavity		observed				References: Sundberg J, MGI Direct Data Submission 2007;():
Mouth - Oral mucosa cyst	Mouth - Oral mucosa		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Muscle - Smooth leiomyoma	Vagina		0				References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Muscle - Smooth leiomyosarcoma	Intestine - Large Intestine - Cecum		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Muscle - Smooth leiomyosarcoma	Muscle - Smooth		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Muscle - Striated - Skeletal lesion	Muscle - Striated - Skeletal				observed		References: Sher RB, PLoS One 2011;6(8):e23498
Muscle - Striated - Skeletal neoplasm	Muscle - Striated - Skeletal				observed		References: Sher RB, PLoS One 2011;6(8):e23498
Muscle - Striated - Skeletal normal tissue (control)	Muscle - Striated - Skeletal			not applicable			References: Sher RB, PLoS One 2011;6(8):e23498
Muscle - Striated - Skeletal rhabdomyosarcoma	Muscle - Striated - Skeletal		0 - observed	observed - low	observed	observed	References: Sher RB, PLoS One 2011;6(8):e23498 ⋅ Sundberg J, MGI Direct Data Submission 2007;(): ⋅ Sundberg J, Personal Communication 1997;(): ⋅ Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1(): 30 pathology image(s)
Muscle - Striated - Skeletal rhabdomyosarcoma	CNS - Spinal cord		observed				References: Sundberg J, Personal Communication 1997;(): 3 pathology image(s)
Muscle - Striated - Skeletal rhabdomyosarcoma	Leg		observed				References: Sundberg J, MGI Direct Data Submission 2007;():
Muscle - Striated - Skeletal rhabdomyosarcoma	Bone - Vertebral column		observed				References: Sundberg J, MGI Direct Data Submission 2007;():
Muscle - Striated - Skeletal rhabdomyosarcoma - pleomorphic	Muscle - Striated - Skeletal		0 - 78.95	0 - 70	0 - 75.86		References: Sher RB, PLoS One 2011;6(8):e23498 16 pathology image(s)
Muscle - Striated - Skeletal rhabdomyosarcoma - well differentiated	Muscle - Striated - Skeletal					observed	References: Sundberg J, Personal Communication 1997;(): 2 pathology image(s)
Muscle - Striated - Skeletal tumor	Muscle - Striated - Skeletal				observed		References: Sher RB, PLoS One 2011;6(8):e23498
Myoepithelial cell myoepithelioma	Myoepithelial cell		1	1		sporadic	References: Festing MFW, Mouse Genome 1996;94(3):523-677 ⋅ Sundberg JP, Vet Pathol 1991 Jul;28(4):313-23
Myoepithelial cell myoepithelioma	Mammary gland		0	0 - observed			References: Sundberg J, MGI Direct Data Submission 2007;(): ⋅ Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1(): Sites of Metastasis: Lung 6 pathology image(s)
Myoepithelial cell myoepithelioma	Blood vessel			observed			References: Sundberg J, MGI Direct Data Submission 2007;(): 1 pathology image(s)
Myoepithelial cell myoepithelioma	Lung		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Nail squamous cell carcinoma	Nail		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Ovary - Follicle cyst - follicular	Ovary - Follicle		0				References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Ovary - Granulosa cell tumor	Ovary - Granulosa cell		1				References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35 Sites of Metastasis: Lung
Ovary - Granulosa cell tumor - granulosa cell	Ovary - Granulosa cell		0				References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Ovary - Luteal cell tumor	Ovary - Luteal cell		0				References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Ovary adenoma	Ovary		0				References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Ovary cyst	Ovary		observed				References: Sundberg J, MGI Direct Data Submission 2007;():
Ovary cyst - bursal	Ovary		0				References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Ovary hyperplasia - epithelial	Ovary		0				References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Ovary tumor - tubulostromal	Ovary		0				References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
PNS - Nerve sheath tumor	Ear		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
PNS - Nerve sheath tumor	Skin		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
PNS - Nerve sheath tumor - malignant	Subcutis		observed				References: Mikaelian I, Personal Communication 2004;(): 9 pathology image(s)
Pancreas - Duct adenoma	Pancreas - Duct		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Pancreas - Islet of Langerhans hyperplasia	Pancreas - Islet of Langerhans		observed				References: Sundberg J, MGI Direct Data Submission 2007;():
Pancreas carcinoma in situ	Pancreas		observed				References: Sundberg J, MGI Direct Data Submission 2007;():
Prostate gland - Anterior lobe adenocarcinoma	Prostate gland - Anterior lobe			0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Salivary gland carcinoma	Salivary gland				1		References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35
Skin - Epidermis - Basal cell carcinoma	Skin - Epidermis - Basal cell		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Skin - Epidermis cyst - inclusion	Skin - Epidermis		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Skin - Vibrissa squamous cell carcinoma in situ	Skin - Vibrissa		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Skin gland - Sweat gland hyperplasia	Ear - Outer ear - Ear canal		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Skin hyperplasia - epithelial	Ear		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Skin hyperplasia - epithelial	Eye - Eyelid		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Skin tumor	Skin	12-O-tetradecanoylphorbol-13-acetate (TPA) ⋅ 7,12-dimethylbenz[a]anthracene (DMBA)				64	References: Sundberg JP, Mol Carcinog 1997 SEP;20(1):19-32
Spleen hyperplasia	Spleen		observed	observed			References: Sundberg J, MGI Direct Data Submission 2007;():
Stomach - Glandular adenoma	Stomach - Glandular		0 - observed	0			References: Sundberg J, MGI Direct Data Submission 2007;(): ⋅ Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Stomach - Glandular cyst	Stomach - Glandular		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Stomach - Glandular cyst - glandular	Stomach - Glandular		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Stomach - Glandular hyperplasia	Stomach - Glandular		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Stomach - Glandular hyperplasia - adenomatous	Stomach - Glandular		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Stomach - Glandular polyp	Stomach - Glandular		0				References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Stomach papilloma	Stomach		observed - low				References: Rioux N, Cancer Res 1998 Dec 1;58(23):5354-60 ⋅ Sundberg J, MGI Direct Data Submission 2007;():
Stomach papilloma	Stomach	4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)	low				References: Rioux N, Cancer Res 1998 Dec 1;58(23):5354-60
Stomach papilloma	Stomach	4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) ⋅ aspirin (acetylsalicylic acid) (ASA)	low				References: Rioux N, Cancer Res 1998 Dec 1;58(23):5354-60
Stomach papilloma	Stomach	acetaminophen ⋅ 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)	low				References: Rioux N, Cancer Res 1998 Dec 1;58(23):5354-60
Stomach papilloma	Stomach	4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) ⋅ NS-398	low				References: Rioux N, Cancer Res 1998 Dec 1;58(23):5354-60
Testis - Leydig cell (Interstitial cell) cyst	Testis - Leydig cell (Interstitial cell)			0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Testis - Leydig cell (Interstitial cell) hyperplasia	Testis - Leydig cell (Interstitial cell)			0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Testis - Leydig cell (Interstitial cell) tumor	Testis - Leydig cell (Interstitial cell)			0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Thymus thymoma	Thymus				1		References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35
Thyroid gland - Follicular cell cyst	Thyroid gland - Follicular cell		observed				References: Sundberg J, MGI Direct Data Submission 2007;():
Thyroid gland hyperplasia - cystic	Thyroid gland		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Ureter - Transitional cell hyperplasia	Ureter - Transitional cell		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Ureter hyperplasia	Muscle - Smooth		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Ureter polyp	Ureter		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Urinary bladder - Transitional cell atypia	Urinary bladder - Transitional cell		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Urinary bladder papilloma	Urinary bladder	uracil mustard			1		References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35
Urinary bladder papilloma	Urinary bladder		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Uterus - Cervix squamous cell carcinoma	Uterus - Cervix		observed				References: Sundberg J, MGI Direct Data Submission 2007;(): 3 pathology image(s)
Uterus - Endometrium hyperplasia - cystic	Uterus - Endometrium		observed - moderate				References: Sundberg J, MGI Direct Data Submission 2007;(): ⋅ Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Uterus adenoma	Uterus		0				References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Uterus fibropapilloma	Uterus		0				References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Vagina papilloma	Vagina		0				References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Vulva squamous cell carcinoma	Vulva		0				References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
(Unspecified organ) tumor	(Unspecified organ)		30	13			References: Storer JB, J Gerontol 1966 Jul;21(3):404-9

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